Newly designed curcumin-loaded hybrid nanoparticles: a multifunctional strategy for combating oxidative stress, inflammation, and infections to accelerate wound healing and tissue regeneration

Newly designed curcumin-loaded hybrid nanoparticles: a multifunctional strategy for combating oxidative stress, inflammation, and infections to accelerate wound healing and tissue regeneration

Abstract Effective treatment of skin wounds remains a clinical challenge owing to factors such as microbial infections, impaired fibroblast activity, disrupted angiogenesis, and collagen remodeling. In this study, we developed and evaluated novel curcumin–cyclodextrin hybrid nanoparticles (Cur/CD-HN...

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Main Authors: Heidi M. Abdel-Mageed, Nermeen Z. AbuelEzz, Ahmed A. Ali, Amira Emad Abdelaziz, Dina Nada, Sahar M. Abdelraouf, Shahinaze A. Fouad, Abeer Bishr, Rasha A. Radwan
Format: Article
Language:English
Published: BMC 2025-06-01
Series:BMC Biotechnology
Subjects:
Curcumin
Hydrogels
Wound healing
Antioxidant anti-inflammatory
Hybrid nanoparticles
Cyclodextrin
Online Access:https://doi.org/10.1186/s12896-025-00989-z
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https://doi.org/10.1186/s12896-025-00989-z

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