Primary Dural Lymphoma Mimicking En Plaque Cerebellopontine Angle Meningioma
Primary dural lymphoma (PDL) usually arises from the calvarial dura without the brain parenchyma or systemic involvement and thus may not be considered as a typical form of primary CNS lymphoma (PCNSL). It is exceedingly rare. When it occurs, it might not be suspected as a primary diagnosis on clini...
Saved in:
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2021-01-01
|
Series: | Case Reports in Pathology |
Online Access: | http://dx.doi.org/10.1155/2021/2845995 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
_version_ | 1832560578288156672 |
---|---|
author | Mei Xu Ashish Bains Yuan Rong |
author_facet | Mei Xu Ashish Bains Yuan Rong |
author_sort | Mei Xu |
collection | DOAJ |
description | Primary dural lymphoma (PDL) usually arises from the calvarial dura without the brain parenchyma or systemic involvement and thus may not be considered as a typical form of primary CNS lymphoma (PCNSL). It is exceedingly rare. When it occurs, it might not be suspected as a primary diagnosis on clinical and radiologic findings. We present a PDL case that occurs at the cerebellopontine (CP) angle mimicking en plaque meningioma. The tumor histopathology showed a lymphoproliferative disorder immunophenotypically consistent with a low-grade marginal zone lymphoma. Bone marrow and systemic involvements were not identified, and a diagnosis of PDL was established. As a residual tumor at the CP angle was inaccessible to surgery, postoperative radiation therapy was performed. No recurrence was found at 15-month follow-up. PDLs are mostly indolent and have a good prognosis. There is no doubt that the most important differential diagnosis is meningioma. Furthermore, the present case emphasizes the necessity of an intraoperative consultation and knowledge of this rare yet essential form of PCNSL so that appropriate studies can be ordered. |
format | Article |
id | doaj-art-1355cb64d34440869aba6a7c22c1ac70 |
institution | Kabale University |
issn | 2090-6781 2090-679X |
language | English |
publishDate | 2021-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Pathology |
spelling | doaj-art-1355cb64d34440869aba6a7c22c1ac702025-02-03T01:27:06ZengWileyCase Reports in Pathology2090-67812090-679X2021-01-01202110.1155/2021/28459952845995Primary Dural Lymphoma Mimicking En Plaque Cerebellopontine Angle MeningiomaMei Xu0Ashish Bains1Yuan Rong2Department of Biomedical Sciences, Philadelphia College of Osteopathic Medicine, Philadelphia, Pennsylvania, USADepartment of Pathology and Laboratory Medicine, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania, USADepartment of Pathology and Laboratory Medicine, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania, USAPrimary dural lymphoma (PDL) usually arises from the calvarial dura without the brain parenchyma or systemic involvement and thus may not be considered as a typical form of primary CNS lymphoma (PCNSL). It is exceedingly rare. When it occurs, it might not be suspected as a primary diagnosis on clinical and radiologic findings. We present a PDL case that occurs at the cerebellopontine (CP) angle mimicking en plaque meningioma. The tumor histopathology showed a lymphoproliferative disorder immunophenotypically consistent with a low-grade marginal zone lymphoma. Bone marrow and systemic involvements were not identified, and a diagnosis of PDL was established. As a residual tumor at the CP angle was inaccessible to surgery, postoperative radiation therapy was performed. No recurrence was found at 15-month follow-up. PDLs are mostly indolent and have a good prognosis. There is no doubt that the most important differential diagnosis is meningioma. Furthermore, the present case emphasizes the necessity of an intraoperative consultation and knowledge of this rare yet essential form of PCNSL so that appropriate studies can be ordered.http://dx.doi.org/10.1155/2021/2845995 |
spellingShingle | Mei Xu Ashish Bains Yuan Rong Primary Dural Lymphoma Mimicking En Plaque Cerebellopontine Angle Meningioma Case Reports in Pathology |
title | Primary Dural Lymphoma Mimicking En Plaque Cerebellopontine Angle Meningioma |
title_full | Primary Dural Lymphoma Mimicking En Plaque Cerebellopontine Angle Meningioma |
title_fullStr | Primary Dural Lymphoma Mimicking En Plaque Cerebellopontine Angle Meningioma |
title_full_unstemmed | Primary Dural Lymphoma Mimicking En Plaque Cerebellopontine Angle Meningioma |
title_short | Primary Dural Lymphoma Mimicking En Plaque Cerebellopontine Angle Meningioma |
title_sort | primary dural lymphoma mimicking en plaque cerebellopontine angle meningioma |
url | http://dx.doi.org/10.1155/2021/2845995 |
work_keys_str_mv | AT meixu primarydurallymphomamimickingenplaquecerebellopontineanglemeningioma AT ashishbains primarydurallymphomamimickingenplaquecerebellopontineanglemeningioma AT yuanrong primarydurallymphomamimickingenplaquecerebellopontineanglemeningioma |