Enhancing Antidepressant Effect of Poloxamer/Chitosan Thermosensitive Gel Containing Curcumin-Cyclodextrin Inclusion Complex

Poor solubility and bioavailability are limiting factors for the clinical application of curcumin. This study seeks to develop poloxamer/chitosan thermosensitive gel containing curcumin-cyclodextrin inclusion complex with enhanced brain bioavailability and antidepressant effect. The optimized gel ha...

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Bibliographic Details
Main Author: Ye Zhang
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:International Journal of Polymer Science
Online Access:http://dx.doi.org/10.1155/2018/3041417
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