Association Between DNA Methylation of MTHFR and Diabetic Kidney Disease

Conclusion: Methylation of the MTHFR gene Exon 2 is a protective factor for DKD and may contribute to its onset and progression through its influence on HCY levels. These findings highlight the potential of MTHFR methylation as a biomarker for DKD.

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Bibliographic Details
Main Authors: Guoxiong Deng, Ziyi Feng, Xiaomu Kong, Peng Gao, Yongwei Jiang, Yi Liu, Meimei Zhao, Liang Ma
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/jdr/8096423
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Summary:Conclusion: Methylation of the MTHFR gene Exon 2 is a protective factor for DKD and may contribute to its onset and progression through its influence on HCY levels. These findings highlight the potential of MTHFR methylation as a biomarker for DKD.
ISSN:2314-6753