Recent Advances in Implantable 3D-Printed Scaffolds for Repair of Spinal Cord Injury
Spinal cord injury (SCI) is an important factor in sensory and motor disorders that affects thousands of people every year. Currently, despite successes in basic science and clinical research, there are few effective methods in the treatment of chronic and acute spinal cord injuries. In the last dec...
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| Format: | Article |
| Language: | English |
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Tabriz University of Medical Sciences
2024-07-01
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| Series: | Advanced Pharmaceutical Bulletin |
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| Online Access: | https://apb.tbzmed.ac.ir/PDF/apb-14-331.pdf |
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| author | Salar Khaledian Ghobad Mohammadi Mohadese Abdoli Arad Fatahian Arya Fatahian Reza Fatahian |
| author_facet | Salar Khaledian Ghobad Mohammadi Mohadese Abdoli Arad Fatahian Arya Fatahian Reza Fatahian |
| author_sort | Salar Khaledian |
| collection | DOAJ |
| description | Spinal cord injury (SCI) is an important factor in sensory and motor disorders that affects thousands of people every year. Currently, despite successes in basic science and clinical research, there are few effective methods in the treatment of chronic and acute spinal cord injuries. In the last decade, the use of 3D printed scaffolds in the treatment of SCI had satisfactory and promising results. By providing a microenvironment around the injury site and in combination with growth factors or cells, 3D printed scaffolds help in axon regeneration as well as neural recovery after SCI. Here, we provide an overview of tissue engineering, 3D printing scaffolds, the different polymers used and their characterization methods. This review highlights the recent encouraging applications of 3D printing scaffolds in developing the novel SCI therapy. |
| format | Article |
| id | doaj-art-131eee74855f416eb02aa86bd4cff665 |
| institution | DOAJ |
| issn | 2228-5881 2251-7308 |
| language | English |
| publishDate | 2024-07-01 |
| publisher | Tabriz University of Medical Sciences |
| record_format | Article |
| series | Advanced Pharmaceutical Bulletin |
| spelling | doaj-art-131eee74855f416eb02aa86bd4cff6652025-08-20T03:11:26ZengTabriz University of Medical SciencesAdvanced Pharmaceutical Bulletin2228-58812251-73082024-07-0114233134510.34172/apb.2024.032apb-42052Recent Advances in Implantable 3D-Printed Scaffolds for Repair of Spinal Cord InjurySalar Khaledian0Ghobad Mohammadi1Mohadese Abdoli2Arad Fatahian3Arya Fatahian4Reza Fatahian5Infectious Diseases Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.Pharmaceutical Sciences Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.Department of Nanobiotechnology, Faculty of Innovative Science and Technology, Razi University, Kermanshah, Iran.School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, Iran.School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, Iran.Clinical Research Development Center, Taleghani and Imam Ali Hospitals, Kermanshah University of Medical Sciences, Kermanshah, Iran.Spinal cord injury (SCI) is an important factor in sensory and motor disorders that affects thousands of people every year. Currently, despite successes in basic science and clinical research, there are few effective methods in the treatment of chronic and acute spinal cord injuries. In the last decade, the use of 3D printed scaffolds in the treatment of SCI had satisfactory and promising results. By providing a microenvironment around the injury site and in combination with growth factors or cells, 3D printed scaffolds help in axon regeneration as well as neural recovery after SCI. Here, we provide an overview of tissue engineering, 3D printing scaffolds, the different polymers used and their characterization methods. This review highlights the recent encouraging applications of 3D printing scaffolds in developing the novel SCI therapy.https://apb.tbzmed.ac.ir/PDF/apb-14-331.pdfhydrogelpolymer-based scaffoldneural protectionfunction recoverycollagensilk |
| spellingShingle | Salar Khaledian Ghobad Mohammadi Mohadese Abdoli Arad Fatahian Arya Fatahian Reza Fatahian Recent Advances in Implantable 3D-Printed Scaffolds for Repair of Spinal Cord Injury Advanced Pharmaceutical Bulletin hydrogel polymer-based scaffold neural protection function recovery collagen silk |
| title | Recent Advances in Implantable 3D-Printed Scaffolds for Repair of Spinal Cord Injury |
| title_full | Recent Advances in Implantable 3D-Printed Scaffolds for Repair of Spinal Cord Injury |
| title_fullStr | Recent Advances in Implantable 3D-Printed Scaffolds for Repair of Spinal Cord Injury |
| title_full_unstemmed | Recent Advances in Implantable 3D-Printed Scaffolds for Repair of Spinal Cord Injury |
| title_short | Recent Advances in Implantable 3D-Printed Scaffolds for Repair of Spinal Cord Injury |
| title_sort | recent advances in implantable 3d printed scaffolds for repair of spinal cord injury |
| topic | hydrogel polymer-based scaffold neural protection function recovery collagen silk |
| url | https://apb.tbzmed.ac.ir/PDF/apb-14-331.pdf |
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