Progress in Prevention and Treatment of Acute Bone Loss in Orthopedics

Orthopedic patients need to perform limb immobilization for several days to several weeks due to fracture or other special circumstances. When the function of a certain part or the whole body is restricted, the activity of osteoclasts will be enhanced and its life activity will surpass that of osteo...

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Main Authors: Haoran Wang, Ji Wu, Boyao Wang, Hu Qin, Lei Fan, Yunhua Wang, Bin He
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2023/9373043
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author Haoran Wang
Ji Wu
Boyao Wang
Hu Qin
Lei Fan
Yunhua Wang
Bin He
author_facet Haoran Wang
Ji Wu
Boyao Wang
Hu Qin
Lei Fan
Yunhua Wang
Bin He
author_sort Haoran Wang
collection DOAJ
description Orthopedic patients need to perform limb immobilization for several days to several weeks due to fracture or other special circumstances. When the function of a certain part or the whole body is restricted, the activity of osteoclasts will be enhanced and its life activity will surpass that of osteoblasts, so local or even whole body bone loss will occur. Acute bone loss usually occurs within a few weeks after the immobilization of limbs. At this stage, the patient’s bone mass will decrease sharply, and the patient is prone to osteoporotic refracture. After that, the bone mass will gradually recover, but the speed of bone formation and bone absorption is difficult to reach a balanced state, and the bone mass of patients will continue to decline after it has recovered to a certain degree. After acute progressive bone loss, a large number of bones were lost and the strength of bones decreased. It is often difficult to recover to the level before fracture for a long time, which undoubtedly increases the risk of osteoporosis and related refractures. According to this common phenomenon of bone loss, clinical treatment varies greatly. After a series of research and practice, clinicians summed up some rules and put forward some feasible suggestions, thus strengthening clinicians’ understanding of the treatment of acute bone loss, effectively improving the treatment effect of acute bone loss, having far-reaching significance for preventing and treating osteoporosis, reducing the risk of fracture, and improving the long-term prognosis of patients.
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publishDate 2023-01-01
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spelling doaj-art-13123e3ea80b4f2588e2708cc5d1f5f22025-08-20T03:55:44ZengWileyInternational Journal of Endocrinology1687-83452023-01-01202310.1155/2023/9373043Progress in Prevention and Treatment of Acute Bone Loss in OrthopedicsHaoran Wang0Ji Wu1Boyao Wang2Hu Qin3Lei Fan4Yunhua Wang5Bin He6Department of OrthopaedicsDepartment of OrthopaedicsDepartment of OrthopaedicsDepartment of OrthopaedicsDepartment of OrthopaedicsDepartment of OrthopaedicsDepartment of OrthopaedicsOrthopedic patients need to perform limb immobilization for several days to several weeks due to fracture or other special circumstances. When the function of a certain part or the whole body is restricted, the activity of osteoclasts will be enhanced and its life activity will surpass that of osteoblasts, so local or even whole body bone loss will occur. Acute bone loss usually occurs within a few weeks after the immobilization of limbs. At this stage, the patient’s bone mass will decrease sharply, and the patient is prone to osteoporotic refracture. After that, the bone mass will gradually recover, but the speed of bone formation and bone absorption is difficult to reach a balanced state, and the bone mass of patients will continue to decline after it has recovered to a certain degree. After acute progressive bone loss, a large number of bones were lost and the strength of bones decreased. It is often difficult to recover to the level before fracture for a long time, which undoubtedly increases the risk of osteoporosis and related refractures. According to this common phenomenon of bone loss, clinical treatment varies greatly. After a series of research and practice, clinicians summed up some rules and put forward some feasible suggestions, thus strengthening clinicians’ understanding of the treatment of acute bone loss, effectively improving the treatment effect of acute bone loss, having far-reaching significance for preventing and treating osteoporosis, reducing the risk of fracture, and improving the long-term prognosis of patients.http://dx.doi.org/10.1155/2023/9373043
spellingShingle Haoran Wang
Ji Wu
Boyao Wang
Hu Qin
Lei Fan
Yunhua Wang
Bin He
Progress in Prevention and Treatment of Acute Bone Loss in Orthopedics
International Journal of Endocrinology
title Progress in Prevention and Treatment of Acute Bone Loss in Orthopedics
title_full Progress in Prevention and Treatment of Acute Bone Loss in Orthopedics
title_fullStr Progress in Prevention and Treatment of Acute Bone Loss in Orthopedics
title_full_unstemmed Progress in Prevention and Treatment of Acute Bone Loss in Orthopedics
title_short Progress in Prevention and Treatment of Acute Bone Loss in Orthopedics
title_sort progress in prevention and treatment of acute bone loss in orthopedics
url http://dx.doi.org/10.1155/2023/9373043
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