Seroprevalence of antibodies to hepatitis A, B and C viruses across all age groups in Chonburi Province, Thailand, 2022–2023
Viral hepatitis is a global challenge, particularly in low- and middle-income countries. The World Health Organization aims to eliminate HBV and HCV by 2030, targeting HBsAg prevalence below 0.1% in children under 5. This study analyzed sera from 1,459 participants of all ages in Chonburi province,...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2025-12-01
|
| Series: | Human Vaccines & Immunotherapeutics |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/21645515.2025.2480403 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850038196682883072 |
|---|---|
| author | Nasamon Wanlapakorn Jira Chansaenroj Preeyaporn Vichaiwattana Sirapa Klinfueng Yong Poovorawan |
| author_facet | Nasamon Wanlapakorn Jira Chansaenroj Preeyaporn Vichaiwattana Sirapa Klinfueng Yong Poovorawan |
| author_sort | Nasamon Wanlapakorn |
| collection | DOAJ |
| description | Viral hepatitis is a global challenge, particularly in low- and middle-income countries. The World Health Organization aims to eliminate HBV and HCV by 2030, targeting HBsAg prevalence below 0.1% in children under 5. This study analyzed sera from 1,459 participants of all ages in Chonburi province, Thailand, between October 2022 and January 2023 to assess whether this target has been met and to evaluate the seroprevalence of anti-HBs, anti-HBc, anti-hepatitis A virus (HAV), and anti-HCV in this population. Participants were healthy individuals with no immunosuppressed status. Results indicated a 0% HBsAg seroprevalence rate among children under 5, while those born before the universal immunization program had a seroprevalence rate of 5.6%. The lowest rate of anti-HBs seropositivity (anti-HBs ≥10 mIU/mL) was observed among adolescents aged 11–20 (31.7%). The anti-HBc seropositivity rate increased with age, following a pattern similar to HBsAg trends. Only a small percentage of subjects (0.3%) tested positive for anti-HCV. The seroprevalence of anti-HAV was below 20% in individuals under 40. These findings suggest that Thailand has met the regional HBsAg seroprevalence targets for children under 5 due to high HepB vaccination coverage and timely birth doses. |
| format | Article |
| id | doaj-art-130d4377ca7a450d859c082bf30125fa |
| institution | DOAJ |
| issn | 2164-5515 2164-554X |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Human Vaccines & Immunotherapeutics |
| spelling | doaj-art-130d4377ca7a450d859c082bf30125fa2025-08-20T02:56:39ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2025-12-0121110.1080/21645515.2025.2480403Seroprevalence of antibodies to hepatitis A, B and C viruses across all age groups in Chonburi Province, Thailand, 2022–2023Nasamon Wanlapakorn0Jira Chansaenroj1Preeyaporn Vichaiwattana2Sirapa Klinfueng3Yong Poovorawan4Center of Excellence in Clinical Virology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, ThailandCenter of Excellence in Clinical Virology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, ThailandCenter of Excellence in Clinical Virology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, ThailandCenter of Excellence in Clinical Virology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, ThailandCenter of Excellence in Clinical Virology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, ThailandViral hepatitis is a global challenge, particularly in low- and middle-income countries. The World Health Organization aims to eliminate HBV and HCV by 2030, targeting HBsAg prevalence below 0.1% in children under 5. This study analyzed sera from 1,459 participants of all ages in Chonburi province, Thailand, between October 2022 and January 2023 to assess whether this target has been met and to evaluate the seroprevalence of anti-HBs, anti-HBc, anti-hepatitis A virus (HAV), and anti-HCV in this population. Participants were healthy individuals with no immunosuppressed status. Results indicated a 0% HBsAg seroprevalence rate among children under 5, while those born before the universal immunization program had a seroprevalence rate of 5.6%. The lowest rate of anti-HBs seropositivity (anti-HBs ≥10 mIU/mL) was observed among adolescents aged 11–20 (31.7%). The anti-HBc seropositivity rate increased with age, following a pattern similar to HBsAg trends. Only a small percentage of subjects (0.3%) tested positive for anti-HCV. The seroprevalence of anti-HAV was below 20% in individuals under 40. These findings suggest that Thailand has met the regional HBsAg seroprevalence targets for children under 5 due to high HepB vaccination coverage and timely birth doses.https://www.tandfonline.com/doi/10.1080/21645515.2025.2480403Seroprevalencehepatitis Ahepatitis Bhepatitis Cpopulation |
| spellingShingle | Nasamon Wanlapakorn Jira Chansaenroj Preeyaporn Vichaiwattana Sirapa Klinfueng Yong Poovorawan Seroprevalence of antibodies to hepatitis A, B and C viruses across all age groups in Chonburi Province, Thailand, 2022–2023 Human Vaccines & Immunotherapeutics Seroprevalence hepatitis A hepatitis B hepatitis C population |
| title | Seroprevalence of antibodies to hepatitis A, B and C viruses across all age groups in Chonburi Province, Thailand, 2022–2023 |
| title_full | Seroprevalence of antibodies to hepatitis A, B and C viruses across all age groups in Chonburi Province, Thailand, 2022–2023 |
| title_fullStr | Seroprevalence of antibodies to hepatitis A, B and C viruses across all age groups in Chonburi Province, Thailand, 2022–2023 |
| title_full_unstemmed | Seroprevalence of antibodies to hepatitis A, B and C viruses across all age groups in Chonburi Province, Thailand, 2022–2023 |
| title_short | Seroprevalence of antibodies to hepatitis A, B and C viruses across all age groups in Chonburi Province, Thailand, 2022–2023 |
| title_sort | seroprevalence of antibodies to hepatitis a b and c viruses across all age groups in chonburi province thailand 2022 2023 |
| topic | Seroprevalence hepatitis A hepatitis B hepatitis C population |
| url | https://www.tandfonline.com/doi/10.1080/21645515.2025.2480403 |
| work_keys_str_mv | AT nasamonwanlapakorn seroprevalenceofantibodiestohepatitisabandcvirusesacrossallagegroupsinchonburiprovincethailand20222023 AT jirachansaenroj seroprevalenceofantibodiestohepatitisabandcvirusesacrossallagegroupsinchonburiprovincethailand20222023 AT preeyapornvichaiwattana seroprevalenceofantibodiestohepatitisabandcvirusesacrossallagegroupsinchonburiprovincethailand20222023 AT sirapaklinfueng seroprevalenceofantibodiestohepatitisabandcvirusesacrossallagegroupsinchonburiprovincethailand20222023 AT yongpoovorawan seroprevalenceofantibodiestohepatitisabandcvirusesacrossallagegroupsinchonburiprovincethailand20222023 |