Shared and distinct peripheral blood immune cell landscape in MCTD, SLE, and pSS

Shared and distinct peripheral blood immune cell landscape in MCTD, SLE, and pSS

Abstract Background Mixed connective tissue disease (MCTD) is a rare autoimmune disease, and little is known about its pathogenesis. Furthermore, MCTD, systemic lupus erythematosus (SLE), and primary Sjögren’s syndrome (pSS) share many clinical, laboratory, and immunological manifestations. This ove...

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Bibliographic Details
Main Authors: Yanling Cui, Huina Zhang, Yaxuan Deng, Orion Fan, Junbang Wang, Zhonggang Xing, Jianping Tang, Wenmin Zhu, Bangdong Gong, Yi Eve Sun
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Cell & Bioscience
Subjects:
Mixed connective tissue disease
Systemic lupus erythematosus
Primary Sjögren’s syndrome
Single-cell RNA sequencing
Immune cell landscape
Online Access:https://doi.org/10.1186/s13578-025-01374-1
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