Optimized Effects of Fisetin and Hydroxychloroquine on ER Stress and Autophagy in Nonalcoholic Fatty Pancreas Disease in Mice

Optimized Effects of Fisetin and Hydroxychloroquine on ER Stress and Autophagy in Nonalcoholic Fatty Pancreas Disease in Mice

Conclusion: Our study reveals that FSN and HCQ effectively combat HFD-induced NAFPD, improving insulin sensitivity and addressing pancreatic fat deposition linked to metabolic syndrome. While HCQ may cause endoplasmic reticulum stress, FSN offers protective effects, supporting their combined use for...

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Main Authors: Mahboobe Sattari, Amin Karimpour, Maryam Akhavan Taheri, Bagher Larijani, Reza Meshkani, Ozra Tabatabaei-Malazy, Ghodratollah Panahi
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/jdr/2795127
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