Molecular Alterations of KIT Oncogene in Gliomas
Gliomas are the most common and devastating primary brain tumours. Despite therapeutic advances, the majority of gliomas do not respond either to chemo or radiotherapy. KIT, a class III receptor tyrosine kinase (RTK), is frequently involved in tumourigenic processes. Currently, KIT constitutes an at...
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Main Authors: | Ana L. Gomes, Jorge S. Reis-Filho, José M. Lopes, Olga Martinho, Maryou B. K. Lambros, Albino Martins, Fernando Schmitt, Fernando Pardal, Rui M. Reis |
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Format: | Article |
Language: | English |
Published: |
Wiley
2007-01-01
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Series: | Cellular Oncology |
Online Access: | http://dx.doi.org/10.1155/2007/926274 |
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