Brown adipocyte exosome - derived C22:6 inhibits the IL-1β signaling pathway to alleviate rheumatoid arthritis

Brown adipocyte exosome - derived C22:6 inhibits the IL-1β signaling pathway to alleviate rheumatoid arthritis

IntroductionRheumatoid arthritis (RA) is an autoimmune disorder characterized by significant disability and teratogenic effects, for which there are few effective curative therapies. Exosomes derived from mesenchymal stem cells (MSCs) exhibit anti-inflammatory and tissue regenerative properties. Thi...

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Bibliographic Details
Main Authors: Rui Jiang, Yuanyuan Huang, Rongcai Ye, Yujian Zhang, Meng Dong, Hanlin Zhang, Ziyu Cheng, Zhi Zhang, Jiaqi Zhang, Qiaoli Zhang, Gang Sun, Wanzhu Jin
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
rheumatoid arthritis
exosome
C22:6
TLR4
IL-1β
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1543288/full
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