Dramatic Metabolic Response to Dual ICI With Chemotherapy in Low PD‐L1 NSCLC Case
ABSTRACT Despite low PD‐L1 (Programmed Death‐ligand 1) expression, this patient exhibited a dramatic positron emission tomography‐computed tomography response to dual immune checkpoint inhibitors with chemotherapy. This case highlights the potential benefits of combination therapy beyond traditional...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-03-01
|
| Series: | Respirology Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/rcr2.70150 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850097681739808768 |
|---|---|
| author | Toshikazu Kumasa Akina Nigi Keisuke Iwamoto Hidetoshi Itani Shigeto Kondou |
| author_facet | Toshikazu Kumasa Akina Nigi Keisuke Iwamoto Hidetoshi Itani Shigeto Kondou |
| author_sort | Toshikazu Kumasa |
| collection | DOAJ |
| description | ABSTRACT Despite low PD‐L1 (Programmed Death‐ligand 1) expression, this patient exhibited a dramatic positron emission tomography‐computed tomography response to dual immune checkpoint inhibitors with chemotherapy. This case highlights the potential benefits of combination therapy beyond traditional PD‐L1‐based treatment selection. |
| format | Article |
| id | doaj-art-12ffe45c17cf4eaaae4b23ec20ce33b3 |
| institution | DOAJ |
| issn | 2051-3380 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | Respirology Case Reports |
| spelling | doaj-art-12ffe45c17cf4eaaae4b23ec20ce33b32025-08-20T02:40:55ZengWileyRespirology Case Reports2051-33802025-03-01133n/an/a10.1002/rcr2.70150Dramatic Metabolic Response to Dual ICI With Chemotherapy in Low PD‐L1 NSCLC CaseToshikazu Kumasa0Akina Nigi1Keisuke Iwamoto2Hidetoshi Itani3Shigeto Kondou4Department of Respiratory Medicine Japanese Red Cross Ise Hospital Ise JapanDepartment of Respiratory Medicine Japanese Red Cross Ise Hospital Ise JapanDepartment of Respiratory Medicine Japanese Red Cross Ise Hospital Ise JapanDepartment of Respiratory Medicine Japanese Red Cross Ise Hospital Ise JapanDepartment of Respiratory Medicine Japanese Red Cross Ise Hospital Ise JapanABSTRACT Despite low PD‐L1 (Programmed Death‐ligand 1) expression, this patient exhibited a dramatic positron emission tomography‐computed tomography response to dual immune checkpoint inhibitors with chemotherapy. This case highlights the potential benefits of combination therapy beyond traditional PD‐L1‐based treatment selection.https://doi.org/10.1002/rcr2.70150ipilimumablow‐PD‐L1expressionlung cancernivolumabPET‐CT |
| spellingShingle | Toshikazu Kumasa Akina Nigi Keisuke Iwamoto Hidetoshi Itani Shigeto Kondou Dramatic Metabolic Response to Dual ICI With Chemotherapy in Low PD‐L1 NSCLC Case Respirology Case Reports ipilimumab low‐PD‐L1expression lung cancer nivolumab PET‐CT |
| title | Dramatic Metabolic Response to Dual ICI With Chemotherapy in Low PD‐L1 NSCLC Case |
| title_full | Dramatic Metabolic Response to Dual ICI With Chemotherapy in Low PD‐L1 NSCLC Case |
| title_fullStr | Dramatic Metabolic Response to Dual ICI With Chemotherapy in Low PD‐L1 NSCLC Case |
| title_full_unstemmed | Dramatic Metabolic Response to Dual ICI With Chemotherapy in Low PD‐L1 NSCLC Case |
| title_short | Dramatic Metabolic Response to Dual ICI With Chemotherapy in Low PD‐L1 NSCLC Case |
| title_sort | dramatic metabolic response to dual ici with chemotherapy in low pd l1 nsclc case |
| topic | ipilimumab low‐PD‐L1expression lung cancer nivolumab PET‐CT |
| url | https://doi.org/10.1002/rcr2.70150 |
| work_keys_str_mv | AT toshikazukumasa dramaticmetabolicresponsetodualiciwithchemotherapyinlowpdl1nsclccase AT akinanigi dramaticmetabolicresponsetodualiciwithchemotherapyinlowpdl1nsclccase AT keisukeiwamoto dramaticmetabolicresponsetodualiciwithchemotherapyinlowpdl1nsclccase AT hidetoshiitani dramaticmetabolicresponsetodualiciwithchemotherapyinlowpdl1nsclccase AT shigetokondou dramaticmetabolicresponsetodualiciwithchemotherapyinlowpdl1nsclccase |