High Prevalence of Depression and Anxiety in Patients with Chronic Respiratory Diseases Admitted to Intensive Care in a Low-Resource Setting

Background: Depression and anxiety are common in patients with chronic respiratory diseases (CRDs), but their prevalence in intensive care settings, particularly in low-resource regions, remains underexplored. Objective: To assess the prevalence and severity of depression and anxiety in patients wit...

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Main Authors: Amun Mustafa, Asifa Karamat, Wajeeha Mustansar Toor, Tehmina Mustafa
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Advances in Respiratory Medicine
Subjects:
Online Access:https://www.mdpi.com/2543-6031/93/3/12
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author Amun Mustafa
Asifa Karamat
Wajeeha Mustansar Toor
Tehmina Mustafa
author_facet Amun Mustafa
Asifa Karamat
Wajeeha Mustansar Toor
Tehmina Mustafa
author_sort Amun Mustafa
collection DOAJ
description Background: Depression and anxiety are common in patients with chronic respiratory diseases (CRDs), but their prevalence in intensive care settings, particularly in low-resource regions, remains underexplored. Objective: To assess the prevalence and severity of depression and anxiety in patients with CRDs admitted to an intensive care unit (ICU) and identify associated factors. Methods: A cross-sectional study was conducted at Gulab Devi Teaching Hospital, Lahore, Pakistan. Adult patients with CRDs admitted to the ICU were assessed using the Hamilton Depression Rating Scale. Statistical analyses included Fisher’s exact test, Mann–Whitney/Kruskal–Wallis tests, and logistic regression. Results: Depression was highly prevalent across all CRD categories: 83%, 89%, 84%, and 93% in obstructive, restrictive, infectious, and other respiratory disease categories, and severe depression in 16%, 18%, 14%, and 37%, respectively. Anxiety symptoms were also widespread (77–100%), with no significant differences across disease groups. Depression was significantly associated with older age (<i>p</i> < 0.001, OR 1.08) and anxiety symptoms (<i>p</i> < 0.001, OR 47.07). Female gender was linked to anxiety (<i>p</i> = 0.034, OR 4.17). Conclusion: The high burden of depression and anxiety in ICU patients with CRDs underscores the need for routine psychiatric screening and integrated mental health care in critical-care settings.
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spelling doaj-art-12fcb39a695d489d9d8a032a7c45229e2025-08-20T03:27:02ZengMDPI AGAdvances in Respiratory Medicine2543-60312025-06-019331210.3390/arm93030012High Prevalence of Depression and Anxiety in Patients with Chronic Respiratory Diseases Admitted to Intensive Care in a Low-Resource SettingAmun Mustafa0Asifa Karamat1Wajeeha Mustansar Toor2Tehmina Mustafa3Department of Medicine, Fatima Memorial Hospital College of Medicine and Dentistry, Lahore 54000, PakistanDepartment of Pulmonology, Gulab Devi Teaching Hospital, Lahore 54000, PakistanDepartment of Pulmonology, Gulab Devi Teaching Hospital, Lahore 54000, PakistanCenter for International Health, Department of Global Public Health and Primary Care, University of Bergen, 5020 Bergen, NorwayBackground: Depression and anxiety are common in patients with chronic respiratory diseases (CRDs), but their prevalence in intensive care settings, particularly in low-resource regions, remains underexplored. Objective: To assess the prevalence and severity of depression and anxiety in patients with CRDs admitted to an intensive care unit (ICU) and identify associated factors. Methods: A cross-sectional study was conducted at Gulab Devi Teaching Hospital, Lahore, Pakistan. Adult patients with CRDs admitted to the ICU were assessed using the Hamilton Depression Rating Scale. Statistical analyses included Fisher’s exact test, Mann–Whitney/Kruskal–Wallis tests, and logistic regression. Results: Depression was highly prevalent across all CRD categories: 83%, 89%, 84%, and 93% in obstructive, restrictive, infectious, and other respiratory disease categories, and severe depression in 16%, 18%, 14%, and 37%, respectively. Anxiety symptoms were also widespread (77–100%), with no significant differences across disease groups. Depression was significantly associated with older age (<i>p</i> < 0.001, OR 1.08) and anxiety symptoms (<i>p</i> < 0.001, OR 47.07). Female gender was linked to anxiety (<i>p</i> = 0.034, OR 4.17). Conclusion: The high burden of depression and anxiety in ICU patients with CRDs underscores the need for routine psychiatric screening and integrated mental health care in critical-care settings.https://www.mdpi.com/2543-6031/93/3/12depressionanxietychronic respiratory diseasesintensive careHamilton Depression Rating Scale
spellingShingle Amun Mustafa
Asifa Karamat
Wajeeha Mustansar Toor
Tehmina Mustafa
High Prevalence of Depression and Anxiety in Patients with Chronic Respiratory Diseases Admitted to Intensive Care in a Low-Resource Setting
Advances in Respiratory Medicine
depression
anxiety
chronic respiratory diseases
intensive care
Hamilton Depression Rating Scale
title High Prevalence of Depression and Anxiety in Patients with Chronic Respiratory Diseases Admitted to Intensive Care in a Low-Resource Setting
title_full High Prevalence of Depression and Anxiety in Patients with Chronic Respiratory Diseases Admitted to Intensive Care in a Low-Resource Setting
title_fullStr High Prevalence of Depression and Anxiety in Patients with Chronic Respiratory Diseases Admitted to Intensive Care in a Low-Resource Setting
title_full_unstemmed High Prevalence of Depression and Anxiety in Patients with Chronic Respiratory Diseases Admitted to Intensive Care in a Low-Resource Setting
title_short High Prevalence of Depression and Anxiety in Patients with Chronic Respiratory Diseases Admitted to Intensive Care in a Low-Resource Setting
title_sort high prevalence of depression and anxiety in patients with chronic respiratory diseases admitted to intensive care in a low resource setting
topic depression
anxiety
chronic respiratory diseases
intensive care
Hamilton Depression Rating Scale
url https://www.mdpi.com/2543-6031/93/3/12
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