Wdr18 is required for Kupffer's vesicle formation and regulation of body asymmetry in zebrafish.

Wdr18 is required for Kupffer's vesicle formation and regulation of body asymmetry in zebrafish.

Correct specification of the left-right (L-R) axis is important for organ morphogenesis. Conserved mechanisms involving cilia rotation inside node-like structures and asymmetric Nodal signaling in the lateral plate mesoderm (LPM), which are important symmetry-breaking events, have been intensively s...

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Bibliographic Details
Main Authors: Wei Gao, Linjie Xu, Rui Guan, Xinxing Liu, Yuxiang Han, Qian Wu, Yi Xiao, Fei Qi, Zuoyan Zhu, Shuo Lin, Bo Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0023386&type=printable
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