Catheter Interventions for Pulmonary Embolism: Mechanical Thrombectomy Versus Thrombolytics

Pulmonary embolism is a debilitating and potentially life-threatening disease characterized by high mortality and long-term adverse outcomes. Traditional treatment options are fraught with serious bleeding risks and incomplete thrombus removal, necessitating the development of innovative treatment s...

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Main Author: Nicolas J. Mouawad
Format: Article
Language:English
Published: Houston Methodist DeBakey Heart & Vascular Center 2024-05-01
Series:Methodist DeBakey Cardiovascular Journal
Subjects:
Online Access:https://account.journal.houstonmethodist.org/index.php/up-j-mdbcj/article/view/1344
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author Nicolas J. Mouawad
author_facet Nicolas J. Mouawad
author_sort Nicolas J. Mouawad
collection DOAJ
description Pulmonary embolism is a debilitating and potentially life-threatening disease characterized by high mortality and long-term adverse outcomes. Traditional treatment options are fraught with serious bleeding risks and incomplete thrombus removal, necessitating the development of innovative treatment strategies. While new interventional approaches offer promising potential for improved outcomes with fewer serious complications, their rapid development and need for more comparative clinical evidence makes it challenging for physicians to select the optimal treatment for each patient among the many options. This review summarizes the current published clinical data for both traditional treatments and more recent interventional approaches indicated for pulmonary embolism. While published studies thus far suggest that these newer interventional devices offer safe and effective options, more data is needed to understand their impact relative to the standard of care. The studies in progress that are anticipated to provide needed evidence are reviewed here since they will be critical for helping physicians make informed treatment choices and potentially driving necessary guideline changes.
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spelling doaj-art-12e55d4dacc844b39c8d46e4afd00d912025-08-20T02:22:17ZengHouston Methodist DeBakey Heart & Vascular CenterMethodist DeBakey Cardiovascular Journal1947-61082024-05-01203364810.14797/mdcvj.13441321Catheter Interventions for Pulmonary Embolism: Mechanical Thrombectomy Versus ThrombolyticsNicolas J. Mouawad0https://orcid.org/0000-0002-8699-0572McLaren Health System, Bay City, MichiganPulmonary embolism is a debilitating and potentially life-threatening disease characterized by high mortality and long-term adverse outcomes. Traditional treatment options are fraught with serious bleeding risks and incomplete thrombus removal, necessitating the development of innovative treatment strategies. While new interventional approaches offer promising potential for improved outcomes with fewer serious complications, their rapid development and need for more comparative clinical evidence makes it challenging for physicians to select the optimal treatment for each patient among the many options. This review summarizes the current published clinical data for both traditional treatments and more recent interventional approaches indicated for pulmonary embolism. While published studies thus far suggest that these newer interventional devices offer safe and effective options, more data is needed to understand their impact relative to the standard of care. The studies in progress that are anticipated to provide needed evidence are reviewed here since they will be critical for helping physicians make informed treatment choices and potentially driving necessary guideline changes.https://account.journal.houstonmethodist.org/index.php/up-j-mdbcj/article/view/1344pulmonary embolismpethrombolyticsmechanical thrombectomy
spellingShingle Nicolas J. Mouawad
Catheter Interventions for Pulmonary Embolism: Mechanical Thrombectomy Versus Thrombolytics
Methodist DeBakey Cardiovascular Journal
pulmonary embolism
pe
thrombolytics
mechanical thrombectomy
title Catheter Interventions for Pulmonary Embolism: Mechanical Thrombectomy Versus Thrombolytics
title_full Catheter Interventions for Pulmonary Embolism: Mechanical Thrombectomy Versus Thrombolytics
title_fullStr Catheter Interventions for Pulmonary Embolism: Mechanical Thrombectomy Versus Thrombolytics
title_full_unstemmed Catheter Interventions for Pulmonary Embolism: Mechanical Thrombectomy Versus Thrombolytics
title_short Catheter Interventions for Pulmonary Embolism: Mechanical Thrombectomy Versus Thrombolytics
title_sort catheter interventions for pulmonary embolism mechanical thrombectomy versus thrombolytics
topic pulmonary embolism
pe
thrombolytics
mechanical thrombectomy
url https://account.journal.houstonmethodist.org/index.php/up-j-mdbcj/article/view/1344
work_keys_str_mv AT nicolasjmouawad catheterinterventionsforpulmonaryembolismmechanicalthrombectomyversusthrombolytics