The competency of the novel through‐the‐scope suture device for gastric mucosal defects: In vivo study in a porcine model (with video)

Abstract Objectives Endoscopic closures of mucosal defects following endoscopic resection can be challenging and time‐consuming. The novel through‐the‐scope suture device has demonstrated acceptable closure times, but its learning curve is still unknown. This study aims to evaluate the number of cas...

Full description

Saved in:
Bibliographic Details
Main Authors: Mamoru Ito, Akira Dobashi, Takanori Tominaga, Toshiki Futakuchi, Naoto Tamai, Machi Suka, Kazuki Sumiyama
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:DEN Open
Subjects:
Online Access:https://doi.org/10.1002/deo2.70037
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850177645470285824
author Mamoru Ito
Akira Dobashi
Takanori Tominaga
Toshiki Futakuchi
Naoto Tamai
Machi Suka
Kazuki Sumiyama
author_facet Mamoru Ito
Akira Dobashi
Takanori Tominaga
Toshiki Futakuchi
Naoto Tamai
Machi Suka
Kazuki Sumiyama
author_sort Mamoru Ito
collection DOAJ
description Abstract Objectives Endoscopic closures of mucosal defects following endoscopic resection can be challenging and time‐consuming. The novel through‐the‐scope suture device has demonstrated acceptable closure times, but its learning curve is still unknown. This study aims to evaluate the number of cases required to achieve competency in this device. Methods Two endoscopists participated; a novice with less than 400 experiences in upper gastrointestinal endoscopy and an expert with over 500 experiences in endoscopic submucosal dissection. Neither endoscopist had previous exposure to the device. In four porcine models, 24 gastric mucosal defects, each 2–4 cm in diameter, were created by endoscopic mucosal resection with ligation. Each endoscopist performed endoscopic closure for 12 mucosal defects with a single through‐the‐scope suture device per lesion. The primary endpoint was the number of cases needed to reach competency, defined as achieving a procedure time below the average closure time reported in the literature. Secondary endpoints included procedure time, complete closure success rates, and incidence of adverse events. Results The mean defect size was 2.9 (±0.2) cm. Competency was achieved after six cases in the expert and seven cases in the novice. The median closure time was 9.0 (interquartile range [IQR]: 6.0–11.0) min for the expert and 8.0 (IQR: 6.2–9.7) min for the novice (p = 0.862). Complete closure success rates were 75.0% (n = 9) for the expert and 83.3% (n = 10) for the novice. No adverse events were reported. Conclusions A small number of cases were required for both expert and novice endoscopists to reach competency in the novel through‐the‐scope suture device.
format Article
id doaj-art-12e29ebff2824d37b550adb32dc49ebc
institution OA Journals
issn 2692-4609
language English
publishDate 2025-04-01
publisher Wiley
record_format Article
series DEN Open
spelling doaj-art-12e29ebff2824d37b550adb32dc49ebc2025-08-20T02:18:56ZengWileyDEN Open2692-46092025-04-0151n/an/a10.1002/deo2.70037The competency of the novel through‐the‐scope suture device for gastric mucosal defects: In vivo study in a porcine model (with video)Mamoru Ito0Akira Dobashi1Takanori Tominaga2Toshiki Futakuchi3Naoto Tamai4Machi Suka5Kazuki Sumiyama6Department of Endoscopy The Jikei University School of Medicine Tokyo JapanDepartment of Endoscopy The Jikei University School of Medicine Tokyo JapanDepartment of Gastroenterology and Hepatology The Jikei University School of Medicine Tokyo JapanDepartment of Endoscopy The Jikei University School of Medicine Tokyo JapanDepartment of Endoscopy The Jikei University School of Medicine Tokyo JapanDepartment of Public Health and Environmental Medicine The Jikei University School of Medicine Tokyo JapanDepartment of Endoscopy The Jikei University School of Medicine Tokyo JapanAbstract Objectives Endoscopic closures of mucosal defects following endoscopic resection can be challenging and time‐consuming. The novel through‐the‐scope suture device has demonstrated acceptable closure times, but its learning curve is still unknown. This study aims to evaluate the number of cases required to achieve competency in this device. Methods Two endoscopists participated; a novice with less than 400 experiences in upper gastrointestinal endoscopy and an expert with over 500 experiences in endoscopic submucosal dissection. Neither endoscopist had previous exposure to the device. In four porcine models, 24 gastric mucosal defects, each 2–4 cm in diameter, were created by endoscopic mucosal resection with ligation. Each endoscopist performed endoscopic closure for 12 mucosal defects with a single through‐the‐scope suture device per lesion. The primary endpoint was the number of cases needed to reach competency, defined as achieving a procedure time below the average closure time reported in the literature. Secondary endpoints included procedure time, complete closure success rates, and incidence of adverse events. Results The mean defect size was 2.9 (±0.2) cm. Competency was achieved after six cases in the expert and seven cases in the novice. The median closure time was 9.0 (interquartile range [IQR]: 6.0–11.0) min for the expert and 8.0 (IQR: 6.2–9.7) min for the novice (p = 0.862). Complete closure success rates were 75.0% (n = 9) for the expert and 83.3% (n = 10) for the novice. No adverse events were reported. Conclusions A small number of cases were required for both expert and novice endoscopists to reach competency in the novel through‐the‐scope suture device.https://doi.org/10.1002/deo2.70037endoscopic closureendoscopic resectiongastric mucosal defectslearning curvesuture device
spellingShingle Mamoru Ito
Akira Dobashi
Takanori Tominaga
Toshiki Futakuchi
Naoto Tamai
Machi Suka
Kazuki Sumiyama
The competency of the novel through‐the‐scope suture device for gastric mucosal defects: In vivo study in a porcine model (with video)
DEN Open
endoscopic closure
endoscopic resection
gastric mucosal defects
learning curve
suture device
title The competency of the novel through‐the‐scope suture device for gastric mucosal defects: In vivo study in a porcine model (with video)
title_full The competency of the novel through‐the‐scope suture device for gastric mucosal defects: In vivo study in a porcine model (with video)
title_fullStr The competency of the novel through‐the‐scope suture device for gastric mucosal defects: In vivo study in a porcine model (with video)
title_full_unstemmed The competency of the novel through‐the‐scope suture device for gastric mucosal defects: In vivo study in a porcine model (with video)
title_short The competency of the novel through‐the‐scope suture device for gastric mucosal defects: In vivo study in a porcine model (with video)
title_sort competency of the novel through the scope suture device for gastric mucosal defects in vivo study in a porcine model with video
topic endoscopic closure
endoscopic resection
gastric mucosal defects
learning curve
suture device
url https://doi.org/10.1002/deo2.70037
work_keys_str_mv AT mamoruito thecompetencyofthenovelthroughthescopesuturedeviceforgastricmucosaldefectsinvivostudyinaporcinemodelwithvideo
AT akiradobashi thecompetencyofthenovelthroughthescopesuturedeviceforgastricmucosaldefectsinvivostudyinaporcinemodelwithvideo
AT takanoritominaga thecompetencyofthenovelthroughthescopesuturedeviceforgastricmucosaldefectsinvivostudyinaporcinemodelwithvideo
AT toshikifutakuchi thecompetencyofthenovelthroughthescopesuturedeviceforgastricmucosaldefectsinvivostudyinaporcinemodelwithvideo
AT naototamai thecompetencyofthenovelthroughthescopesuturedeviceforgastricmucosaldefectsinvivostudyinaporcinemodelwithvideo
AT machisuka thecompetencyofthenovelthroughthescopesuturedeviceforgastricmucosaldefectsinvivostudyinaporcinemodelwithvideo
AT kazukisumiyama thecompetencyofthenovelthroughthescopesuturedeviceforgastricmucosaldefectsinvivostudyinaporcinemodelwithvideo
AT mamoruito competencyofthenovelthroughthescopesuturedeviceforgastricmucosaldefectsinvivostudyinaporcinemodelwithvideo
AT akiradobashi competencyofthenovelthroughthescopesuturedeviceforgastricmucosaldefectsinvivostudyinaporcinemodelwithvideo
AT takanoritominaga competencyofthenovelthroughthescopesuturedeviceforgastricmucosaldefectsinvivostudyinaporcinemodelwithvideo
AT toshikifutakuchi competencyofthenovelthroughthescopesuturedeviceforgastricmucosaldefectsinvivostudyinaporcinemodelwithvideo
AT naototamai competencyofthenovelthroughthescopesuturedeviceforgastricmucosaldefectsinvivostudyinaporcinemodelwithvideo
AT machisuka competencyofthenovelthroughthescopesuturedeviceforgastricmucosaldefectsinvivostudyinaporcinemodelwithvideo
AT kazukisumiyama competencyofthenovelthroughthescopesuturedeviceforgastricmucosaldefectsinvivostudyinaporcinemodelwithvideo