Metabolism of fat in subacute combined degeneration of the spinal cord
In 10 cases of subacute combined degeneration of the spinal cord the absorption, clearance and utilization of labeled fat was studied. In 4 cases disorders of the lipid metabolism were found. Although not significantly, the peripheral and dorsal funiculi syndromes were more severe in the 4 cases wit...
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| Format: | Article |
| Language: | English |
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Thieme Revinter Publicações
1966-03-01
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| Series: | Arquivos de Neuro-Psiquiatria |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1966000100001&lng=en&tlng=en |
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| _version_ | 1849702708427096064 |
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| author | Horacio M. Canelas Nelson de Carvalho Arnaldo Gama da Rocha |
| author_facet | Horacio M. Canelas Nelson de Carvalho Arnaldo Gama da Rocha |
| author_sort | Horacio M. Canelas |
| collection | DOAJ |
| description | In 10 cases of subacute combined degeneration of the spinal cord the absorption, clearance and utilization of labeled fat was studied. In 4 cases disorders of the lipid metabolism were found. Although not significantly, the peripheral and dorsal funiculi syndromes were more severe in the 4 cases with impaired fat metabolism than in the normal cases, while the pyramidal syndrome was almost the same in the two groups. The whole neurological picture was also more severe in the 4 cases with disorders of fat metabolism. These results seem to indicate that the impairment of lipid metabolism evidenced in such cases bears no direct relationship with the demyelinating process in general, and would rather attend a deficiency of metabolites (probably B-complex vitamins) other than vitamin B12, which play a more significant role in the preservation of the peripheral nerves. |
| format | Article |
| id | doaj-art-12e23741fb8346ad818c4305cc85f601 |
| institution | DOAJ |
| issn | 1678-4227 |
| language | English |
| publishDate | 1966-03-01 |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-12e23741fb8346ad818c4305cc85f6012025-08-20T03:17:32ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42271966-03-012411610.1590/S0004-282X1966000100001S0004-282X1966000100001Metabolism of fat in subacute combined degeneration of the spinal cordHoracio M. CanelasNelson de Carvalho0Arnaldo Gama da RochaUniversidade de São PauloIn 10 cases of subacute combined degeneration of the spinal cord the absorption, clearance and utilization of labeled fat was studied. In 4 cases disorders of the lipid metabolism were found. Although not significantly, the peripheral and dorsal funiculi syndromes were more severe in the 4 cases with impaired fat metabolism than in the normal cases, while the pyramidal syndrome was almost the same in the two groups. The whole neurological picture was also more severe in the 4 cases with disorders of fat metabolism. These results seem to indicate that the impairment of lipid metabolism evidenced in such cases bears no direct relationship with the demyelinating process in general, and would rather attend a deficiency of metabolites (probably B-complex vitamins) other than vitamin B12, which play a more significant role in the preservation of the peripheral nerves.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1966000100001&lng=en&tlng=en |
| spellingShingle | Horacio M. Canelas Nelson de Carvalho Arnaldo Gama da Rocha Metabolism of fat in subacute combined degeneration of the spinal cord Arquivos de Neuro-Psiquiatria |
| title | Metabolism of fat in subacute combined degeneration of the spinal cord |
| title_full | Metabolism of fat in subacute combined degeneration of the spinal cord |
| title_fullStr | Metabolism of fat in subacute combined degeneration of the spinal cord |
| title_full_unstemmed | Metabolism of fat in subacute combined degeneration of the spinal cord |
| title_short | Metabolism of fat in subacute combined degeneration of the spinal cord |
| title_sort | metabolism of fat in subacute combined degeneration of the spinal cord |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1966000100001&lng=en&tlng=en |
| work_keys_str_mv | AT horaciomcanelas metabolismoffatinsubacutecombineddegenerationofthespinalcord AT nelsondecarvalho metabolismoffatinsubacutecombineddegenerationofthespinalcord AT arnaldogamadarocha metabolismoffatinsubacutecombineddegenerationofthespinalcord |