TCL1A in naïve B cells as a therapeutic target for type 1 diabetesResearch in context

TCL1A in naïve B cells as a therapeutic target for type 1 diabetesResearch in context

Summary: Background: Type 1 diabetes (T1D) is an autoimmune disease characterised by the attack of pancreatic β cells by “self” immune cells. Although previous studies demonstrated that B cells contribute to T1D through antigen presentation and autoantibody production, the involvement of different...

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Main Authors: Siweier Luo, Lina Zhang, Chunfang Wei, Chipeng Guo, Zhe Meng, Honghui Zeng, Lele Hou, Le Wang, Zulin Liu, Yufei Du, Shiyu Tan, Yating Zhang, Xiaoding Xu, Liyang Liang, Yiming Zhou
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:EBioMedicine
Subjects:
Type 1 diabetes
Single-cell RNA-sequencing
B cell
TCL1
AKT signalling
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396425000374
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