Burden of Dengue–Typhoid Coinfection in Pediatric Patients: A 6-year Experience from a Tertiary Care Center

Background: India is endemic to both typhoid and dengue, which also mimic in their clinical presentations. This poses a diagnostic dilemma especially for pediatric patients. Literature on such coinfections is limited. Methodology: We retrospectively analyzed six years data (2017–2022). All pediatric...

Full description

Saved in:
Bibliographic Details
Main Authors: Aravinda Anjana, Ranjeeta Adhikary, Malavalli V Bhavana
Format: Article
Language:English
Published: Jaypee Brothers Medical Publisher 2023-06-01
Series:Pediatric Infectious Disease
Subjects:
Online Access:https://www.pidjournal.com/doi/PID/pdf/10.5005/jp-journals-10081-1375
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849236804967858176
author Aravinda Anjana
Ranjeeta Adhikary
Malavalli V Bhavana
author_facet Aravinda Anjana
Ranjeeta Adhikary
Malavalli V Bhavana
author_sort Aravinda Anjana
collection DOAJ
description Background: India is endemic to both typhoid and dengue, which also mimic in their clinical presentations. This poses a diagnostic dilemma especially for pediatric patients. Literature on such coinfections is limited. Methodology: We retrospectively analyzed six years data (2017–2022). All pediatric culture proven typhoid cases with concurrent dengue infection were included in the study. Patient clinical and demographic profiles were extracted from the hospital information system. Results: We report four such cases of coinfection. Along with the expected reduced platelet counts, most of the patients had associated deranged TLC, liver enzymes, hypoalbuminemia and gallbladder changes. Conclusion: Our study contributes to the body of literature on dengue–typhoid coinfection in pediatric patients and the pitfall in accepting a single pathogen etiology. Awareness needs to be raised among healthcare workers on the potential dengue–typhoid coinfection, especially in endemic countries.
format Article
id doaj-art-12dfd88a0cbf4a1d82b665dffc7e7a96
institution Kabale University
issn 2582-4988
language English
publishDate 2023-06-01
publisher Jaypee Brothers Medical Publisher
record_format Article
series Pediatric Infectious Disease
spelling doaj-art-12dfd88a0cbf4a1d82b665dffc7e7a962025-08-20T04:02:09ZengJaypee Brothers Medical PublisherPediatric Infectious Disease2582-49882023-06-0152424410.5005/jp-journals-10081-13752Burden of Dengue–Typhoid Coinfection in Pediatric Patients: A 6-year Experience from a Tertiary Care CenterAravinda Anjana0Ranjeeta Adhikary1Malavalli V Bhavana2Aravinda Anjana, Department of Laboratory Medicine, Manipal Hospitals, Bengaluru, Karnataka, India, Phone: +91 9560348696Department of Laboratory Medicine, Manipal Hospitals, Bengaluru, Karnataka, IndiaDepartment of Laboratory Medicine, Manipal Hospitals, Bengaluru, Karnataka, IndiaBackground: India is endemic to both typhoid and dengue, which also mimic in their clinical presentations. This poses a diagnostic dilemma especially for pediatric patients. Literature on such coinfections is limited. Methodology: We retrospectively analyzed six years data (2017–2022). All pediatric culture proven typhoid cases with concurrent dengue infection were included in the study. Patient clinical and demographic profiles were extracted from the hospital information system. Results: We report four such cases of coinfection. Along with the expected reduced platelet counts, most of the patients had associated deranged TLC, liver enzymes, hypoalbuminemia and gallbladder changes. Conclusion: Our study contributes to the body of literature on dengue–typhoid coinfection in pediatric patients and the pitfall in accepting a single pathogen etiology. Awareness needs to be raised among healthcare workers on the potential dengue–typhoid coinfection, especially in endemic countries.https://www.pidjournal.com/doi/PID/pdf/10.5005/jp-journals-10081-1375coinfectiondenguetyphoid
spellingShingle Aravinda Anjana
Ranjeeta Adhikary
Malavalli V Bhavana
Burden of Dengue–Typhoid Coinfection in Pediatric Patients: A 6-year Experience from a Tertiary Care Center
Pediatric Infectious Disease
coinfection
dengue
typhoid
title Burden of Dengue–Typhoid Coinfection in Pediatric Patients: A 6-year Experience from a Tertiary Care Center
title_full Burden of Dengue–Typhoid Coinfection in Pediatric Patients: A 6-year Experience from a Tertiary Care Center
title_fullStr Burden of Dengue–Typhoid Coinfection in Pediatric Patients: A 6-year Experience from a Tertiary Care Center
title_full_unstemmed Burden of Dengue–Typhoid Coinfection in Pediatric Patients: A 6-year Experience from a Tertiary Care Center
title_short Burden of Dengue–Typhoid Coinfection in Pediatric Patients: A 6-year Experience from a Tertiary Care Center
title_sort burden of dengue typhoid coinfection in pediatric patients a 6 year experience from a tertiary care center
topic coinfection
dengue
typhoid
url https://www.pidjournal.com/doi/PID/pdf/10.5005/jp-journals-10081-1375
work_keys_str_mv AT aravindaanjana burdenofdenguetyphoidcoinfectioninpediatricpatientsa6yearexperiencefromatertiarycarecenter
AT ranjeetaadhikary burdenofdenguetyphoidcoinfectioninpediatricpatientsa6yearexperiencefromatertiarycarecenter
AT malavallivbhavana burdenofdenguetyphoidcoinfectioninpediatricpatientsa6yearexperiencefromatertiarycarecenter