Real world effectiveness of early ensitrelvir treatment in patients with SARS-CoV-2, a retrospective case series

Real world effectiveness of early ensitrelvir treatment in patients with SARS-CoV-2, a retrospective case series

Background: Ensitrelvir, a 3C-like protease inhibitor, received emergency approval in Japan in November 2022 for treating non-hospitalized patients with mild-to-moderate COVID-19. However, confirmation of its real-world clinical effectiveness is limited. Methods: This retrospective study evaluated 1...

Full description

Saved in:

Bibliographic Details
Main Authors:	Shuichi Abe, Dhammika Leshan Wannigama, Yu Suzuki, Daisuke Akaneya, Junko Igarashi, Mayu Suto, Kazunori Moriya, Daisuke Ishizawa, Yoshikazu Okuma, Parichart Hongsing, Cameron Hurst, Thammakorn Saethang, Paul G. Higgins, Stephen M. Stick, Anthony Kicic
Format:	Article
Language:	English
Published:	Elsevier 2024-12-01
Series:	New Microbes and New Infections
Online Access:	http://www.sciencedirect.com/science/article/pii/S2052297524003068
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Identifying High-Risk Bacteria with Active Nasal Swab Surveillance in Intensive Care Units to Prevent Ventilator-Associated Pneumonia
by: Yu Kuramasu, et al.
Published: (2025-04-01)

Antibiotic resistance genes in rural public places mirror the pattern of clinical antibiotic resistance prevalence
by: Dhammika Leshan Wannigama, et al.
Published: (2024-12-01)

Treatment outcome of tuberculosis in a rural area of Japan
by: Ayaka Tateno, et al.
Published: (2024-12-01)

Combination of curcumin or chitosan with photodynamic therapy as an effective alternative therapy for overcoming wound infection associated with multidrug-resistant Acinetobacter baumannii
by: Manta Yonpiam, et al.
Published: (2025-06-01)

First human case of Eidernor doerrieniae colonization in a peritoneal dialysis catheter: A warning from silent contamination
by: Phichit Songviriyavithaya, et al.
Published: (2025-03-01)

Effectiveness of ensitrelvir for cough caused by COVID-19 Omicron variant in patients with asthma
by: Naoyuki Miyashita, et al.
Published: (2025-05-01)

Impact of COVID-19 Vaccination in Thailand: Averted Deaths and Severe Infections Across Age Groups
by: Chaiwat Wilasang, et al.
Published: (2024-11-01)

tesG expression as a potential clinical biomarker for chronic Pseudomonas aeruginosa pulmonary biofilm infections
by: Dhammika Leshan Wannigama, et al.
Published: (2025-03-01)

Alcohol-induced gut permeability defect through dysbiosis and enterocytic mitochondrial interference causing pro-inflammatory macrophages in a dose dependent manner
by: Wiwat Chancharoenthana, et al.
Published: (2025-04-01)

Ensitrelvir as a novel treatment option for mild-to-moderate COVID-19: a narrative literature review
by: Hiroshi Mukae, et al.
Published: (2025-04-01)

Surveillance of avian influenza through bird guano in remote regions of the global south to uncover transmission dynamics
by: Dhammika Leshan Wannigama, et al.
Published: (2025-05-01)

Characterization of an unusual SARS-CoV-2 main protease natural variant exhibiting resistance to nirmatrelvir and ensitrelvir
by: Dipendra Bhandari, et al.
Published: (2025-07-01)

Monolaurin inhibits antibiotic-resistant Staphylococcus aureus in patients with atopic dermatitis
by: Matchima Laowansiri, et al.
Published: (2025-07-01)

Ensitrelvir in Hospitalized Patients with SARS-CoV-2 During the Omicron Epidemic: A Single-Center Observational Study
by: Masaya Yamato, et al.
Published: (2025-04-01)

Drug-drug interaction between ensitrelvir and tacrolimus in a patient undergoing treatment for COVID-19: a case report
by: Yuki Miyata, et al.
Published: (2025-01-01)

Synthetic and Functional Engineering of Bacteriophages: Approaches for Tailored Bactericidal, Diagnostic, and Delivery Platforms
by: Ola Alessa, et al.
Published: (2025-07-01)

Study of key residues in MERS-CoV and SARS-CoV-2 main proteases for resistance against clinically applied inhibitors nirmatrelvir and ensitrelvir
by: Laura Krismer, et al.
Published: (2024-06-01)

Erratum: Z_{2} Dirac points with topologically protected multihelicoid surface states [Phys. Rev. Research 4, 033170 (2022)]
by: Tiantian Zhang, et al.
Published: (2025-06-01)

Inhibitory effects of benzyl isothiocyanate on widespread mcr-1-harbouring IncX4 plasmid transfer
by: Sirirat Luk-In, et al.
Published: (2025-04-01)

Complex multimorbidity and mortality in Japan: a prospective propensity-matched cohort study
by: Ichiro Kawachi, et al.
Published: (2021-08-01)

Azithromycin mitigates human rhinovirus impact on barrier integrity and function in non-diseased airway epithelium
by: Kevin Looi, et al.
Published: (2025-06-01)

Structural and functional properties of bacterial communities associated with rootless duckweed (Wolffia globosa) and their effect on the Wolffia growth
by: Yuparat Saimee, et al.
Published: (2025-08-01)

Advantage of magnifying narrow‐band imaging for the diagnosis of colorectal neoplasia associated with sessile serrated lesions
by: Yuri Enomoto, et al.
Published: (2024-04-01)

Risk Factors for the Requirement of Antenatal Insulin Treatment in Gestational Diabetes Mellitus
by: Mayu Watanabe, et al.
Published: (2016-01-01)

Innate epithelial and functional differences in airway epithelium of children with acute wheeze
by: Kevin Looi, et al.
Published: (2025-07-01)

Deterioration and Manifestation of Cerebral Fat Embolism Triggered by Bone Reaming During Femur Fracture Surgery: A Case Report
by: Daisuke Nakada, et al.
Published: (2025-08-01)

Main right hepatic duct entering the cystic duct: a case report
by: Toshiya Abe, et al.
Published: (2019-03-01)

Assessing the Fiscal Burden of Overweight and Obesity in Japan through Application of a Public Economic Framework
by: Ataru Igarashi, et al.
Published: (2024-11-01)

Peptidoglycan from fermentation by-product triggers defense responses in grapevine.
by: Yang Chen, et al.
Published: (2014-01-01)

A case of vascular Ehlers–Danlos syndrome with a ruptured hepatic artery after surgical treatment of peritonitis caused by the perforation of the colon
by: Daisuke Kakinuma, et al.
Published: (2021-03-01)

Lattice-matched antiperovskite-perovskite system toward all-solid-state batteries
by: Daisuke Ito, et al.
Published: (2025-08-01)

Length Estimation of Pneumatic Artificial Muscle with Optical Fiber Sensor Using Machine Learning
by: Yilei Ni, et al.
Published: (2025-04-01)

Reducing Infectious Complications and Healthcare Costs in Transrectal Ultrasound-Guided Prostate Biopsy with Single-Dose Cefmetazole and Levofloxacin
by: Katsuhiro Onishi, et al.
Published: (2024-12-01)

Visceral Fat Accumulation Is Associated with Asthma in Patients with Type 2 Diabetes
by: Daisuke Murakami, et al.
Published: (2019-01-01)

Gut Dysbiosis in Patients With Fontan Circulation
by: Hideo Ohuchi, et al.
Published: (2024-09-01)

Recent trends in migration flows from the United States to Canada
by: Feng Hou, et al.
Published: (2025-03-01)

A high-throughput colorimetric screening assay for terpene synthase activity based on substrate consumption.
by: Maiko Furubayashi, et al.
Published: (2014-01-01)

Preoperative Cognitive Optimization and Postoperative Cognitive Outcomes: A Narrative Review
by: Ishizawa Y
Published: (2025-03-01)

First genomic analysis of a Clostridium perfringens strain carrying both the cpe and netB genes and the proposal of an amended toxin-based typing scheme
by: Takashi Mada, et al.
Published: (2025-05-01)

<i>ChatGPT Told Me to Say It:</i> AI Chatbots and Class Participation Apprehension in University Students
by: Daisuke Akiba
Published: (2025-07-01)