Current status and perspectives of esophageal cancer: a comprehensive review

Abstract Esophageal cancer (EC) continues to be a significant global health concern, with two main subtypes: esophageal squamous cell carcinoma and esophageal adenocarcinoma. Prevention and changes in etiology, improvements in early detection, and refinements in the treatment have led to remarkable...

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Main Authors: Wei Jiang, Bo Zhang, Jiaqi Xu, Liyan Xue, Luhua Wang
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Cancer Communications
Subjects:
Online Access:https://doi.org/10.1002/cac2.12645
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author Wei Jiang
Bo Zhang
Jiaqi Xu
Liyan Xue
Luhua Wang
author_facet Wei Jiang
Bo Zhang
Jiaqi Xu
Liyan Xue
Luhua Wang
author_sort Wei Jiang
collection DOAJ
description Abstract Esophageal cancer (EC) continues to be a significant global health concern, with two main subtypes: esophageal squamous cell carcinoma and esophageal adenocarcinoma. Prevention and changes in etiology, improvements in early detection, and refinements in the treatment have led to remarkable progress in the outcomes of EC patients in the past two decades. This seminar provides an in‐depth analysis of advances in the epidemiology, disease biology, screening, diagnosis, and treatment landscape of esophageal cancer, focusing on the ongoing debate surrounding multimodality therapy. Despite significant advancements, EC remains a deadly disease, underscoring the need for continued research into early detection methods, understanding the molecular mechanisms, and developing effective treatments.
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institution Kabale University
issn 2523-3548
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publishDate 2025-03-01
publisher Wiley
record_format Article
series Cancer Communications
spelling doaj-art-12d7abb90d22479f9b5f2ac7c9e3ad1e2025-08-20T03:43:55ZengWileyCancer Communications2523-35482025-03-0145328133110.1002/cac2.12645Current status and perspectives of esophageal cancer: a comprehensive reviewWei Jiang0Bo Zhang1Jiaqi Xu2Liyan Xue3Luhua Wang4Department of Radiation Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Shenzhen Guangdong P. R. ChinaDepartment of Medical Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing P. R. ChinaDepartment of Pathology National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing P. R. ChinaDepartment of Pathology National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing P. R. ChinaDepartment of Radiation Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Shenzhen Guangdong P. R. ChinaAbstract Esophageal cancer (EC) continues to be a significant global health concern, with two main subtypes: esophageal squamous cell carcinoma and esophageal adenocarcinoma. Prevention and changes in etiology, improvements in early detection, and refinements in the treatment have led to remarkable progress in the outcomes of EC patients in the past two decades. This seminar provides an in‐depth analysis of advances in the epidemiology, disease biology, screening, diagnosis, and treatment landscape of esophageal cancer, focusing on the ongoing debate surrounding multimodality therapy. Despite significant advancements, EC remains a deadly disease, underscoring the need for continued research into early detection methods, understanding the molecular mechanisms, and developing effective treatments.https://doi.org/10.1002/cac2.12645Comprehensive review Esophageal cancerPathological characteristicsPrevention and ScreeningTreatment advancements
spellingShingle Wei Jiang
Bo Zhang
Jiaqi Xu
Liyan Xue
Luhua Wang
Current status and perspectives of esophageal cancer: a comprehensive review
Cancer Communications
Comprehensive review 
Esophageal cancer
Pathological characteristics
Prevention and Screening
Treatment advancements
title Current status and perspectives of esophageal cancer: a comprehensive review
title_full Current status and perspectives of esophageal cancer: a comprehensive review
title_fullStr Current status and perspectives of esophageal cancer: a comprehensive review
title_full_unstemmed Current status and perspectives of esophageal cancer: a comprehensive review
title_short Current status and perspectives of esophageal cancer: a comprehensive review
title_sort current status and perspectives of esophageal cancer a comprehensive review
topic Comprehensive review 
Esophageal cancer
Pathological characteristics
Prevention and Screening
Treatment advancements
url https://doi.org/10.1002/cac2.12645
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AT liyanxue currentstatusandperspectivesofesophagealcanceracomprehensivereview
AT luhuawang currentstatusandperspectivesofesophagealcanceracomprehensivereview