Modulation of interleukins 38 and 1 Beta gene expression by N-(4-benzoylphenyl)-5-nitrofuran-2-carboxamide in Triton WR-1339 induced hyperlipidemic rats

Modulation of interleukins 38 and 1 Beta gene expression by N-(4-benzoylphenyl)-5-nitrofuran-2-carboxamide in Triton WR-1339 induced hyperlipidemic rats

Abstract Background Atherosclerosis (AS) is characterized by a gradual plaque buildup within the arteries, resulting in hardened and narrowed arteries. Thus, it leads to blood flow limitation and increased risk of critical diseases. Hyperlipidemia is correlated with inflammation, as seen with increa...

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Main Authors: Mohammad Alwahsh, Lama Hamadneh, Suhair Hikmat, Yasmeen Zaid Al-Kilani, Aya Hasan, Sameer Al-Kouz, Rahaf Alejel, Yusuf Al-Hiari, Arwa R. Althaher, Basmah Al-Jammal, Buthaina Hussein, Tariq Al-Qirim
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Lipids in Health and Disease
Subjects:
Hyperlipidemia
Atherosclerosis (AS)
Inflammatory markers
Interleukins
Pro-inflammatory cytokines
Carboxamide derivatives
Online Access:https://doi.org/10.1186/s12944-025-02624-4
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