Could a hand-held, visual electrophysiology device theoretically reduce diagnostic waiting times for complex eye conditions in the NHS? A Discrete Event Simulation (DES) modelling study

Abstract Background/objectives Visual Electro-Diagnostic Testing (EDTs) are a highly specialised service in the NHS. The high cost of tests and a paucity of trained visual electrophysiologists has resulted in very few services across the UK and, when combined with increasing patient backlogs, has ca...

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Main Authors: Steffen Bayer, Daniel Garillo, Marion Penn, Maria Chorozoglou, Sally Brailsford, Eloise Keeling, Fatima Shawkat, Perry Carter, Helena Lee, Jay E. Self
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Health Services Research
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Online Access:https://doi.org/10.1186/s12913-025-12551-w
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author Steffen Bayer
Daniel Garillo
Marion Penn
Maria Chorozoglou
Sally Brailsford
Eloise Keeling
Fatima Shawkat
Perry Carter
Helena Lee
Jay E. Self
author_facet Steffen Bayer
Daniel Garillo
Marion Penn
Maria Chorozoglou
Sally Brailsford
Eloise Keeling
Fatima Shawkat
Perry Carter
Helena Lee
Jay E. Self
author_sort Steffen Bayer
collection DOAJ
description Abstract Background/objectives Visual Electro-Diagnostic Testing (EDTs) are a highly specialised service in the NHS. The high cost of tests and a paucity of trained visual electrophysiologists has resulted in very few services across the UK and, when combined with increasing patient backlogs, has caused significant travel burden and variable waiting times. Here, we study the potential for impact on patients and services by adding a screening step to traditional referral pathways using an Electroretinogram (ERG) test from a relatively inexpensive, portable, hand-held EDT device; the RETeval® (LKC technologies, Gaithersburg, MD, USA). Subjects/methods We model a large regional-referral EDT service using Discrete Event Simulation (DES) modelling based on retrospective patient data and published best evidence for the device. We evaluate the potential impact that adding the screening step in referral pathways could have on patient waiting times should the device prove to be safe and useable in clinical practice. Results We demonstrate that should the RETeval® ERG be safe and useable in real-world clinical practice, it has the potential to significantly reduce patient waiting times by avoiding lab-based EDT assessment for up to 45% of patients. We also show that the impact on services and patients is likely to be resilient to realistic changes in referral numbers, sensitivity/specificity of the device and changes in clinical capacity. Conclusions This work demonstrates that a RETeval® ERG screening step, performed at the point of referral, has the potential to result in significantly reduced EDT waiting lists through fewer patients requiring lab-based EDT assessment and that DES modelling is a useful tool in making this assessment. However, many questions remain about using the device in the real-world setting for this purpose. Future studies are needed to assess its sensitivity/specificity, test/retest variability, changes in referral patterns due to the device, useability, acceptability to patients and importantly, the consequences of screening errors. Our work, using only retrospective data and a DES model, shows that using the device as an ERG screening tool warrants further investigation due to the potential impact on both patients and clinical services.
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spelling doaj-art-12d50416dbc849408ffe476aba30e1ef2025-08-20T03:37:29ZengBMCBMC Health Services Research1472-69632025-03-0125111010.1186/s12913-025-12551-wCould a hand-held, visual electrophysiology device theoretically reduce diagnostic waiting times for complex eye conditions in the NHS? A Discrete Event Simulation (DES) modelling studySteffen Bayer0Daniel Garillo1Marion Penn2Maria Chorozoglou3Sally Brailsford4Eloise Keeling5Fatima Shawkat6Perry Carter7Helena Lee8Jay E. Self9Southampton Business School, University of SouthamptonSouthampton Business School, University of SouthamptonSouthampton Business School, University of SouthamptonSouthampton Health Technology Assessments Centre, Faculty of Medicine, University of SouthamptonSouthampton Business School, University of SouthamptonClinical and Experimental Sciences, Faculty of Medicine, University of SouthamptonOphthalmology Department, University Hospital SouthamptonOphthalmology Department, University Hospital SouthamptonClinical and Experimental Sciences, Faculty of Medicine, University of SouthamptonClinical and Experimental Sciences, Faculty of Medicine, University of SouthamptonAbstract Background/objectives Visual Electro-Diagnostic Testing (EDTs) are a highly specialised service in the NHS. The high cost of tests and a paucity of trained visual electrophysiologists has resulted in very few services across the UK and, when combined with increasing patient backlogs, has caused significant travel burden and variable waiting times. Here, we study the potential for impact on patients and services by adding a screening step to traditional referral pathways using an Electroretinogram (ERG) test from a relatively inexpensive, portable, hand-held EDT device; the RETeval® (LKC technologies, Gaithersburg, MD, USA). Subjects/methods We model a large regional-referral EDT service using Discrete Event Simulation (DES) modelling based on retrospective patient data and published best evidence for the device. We evaluate the potential impact that adding the screening step in referral pathways could have on patient waiting times should the device prove to be safe and useable in clinical practice. Results We demonstrate that should the RETeval® ERG be safe and useable in real-world clinical practice, it has the potential to significantly reduce patient waiting times by avoiding lab-based EDT assessment for up to 45% of patients. We also show that the impact on services and patients is likely to be resilient to realistic changes in referral numbers, sensitivity/specificity of the device and changes in clinical capacity. Conclusions This work demonstrates that a RETeval® ERG screening step, performed at the point of referral, has the potential to result in significantly reduced EDT waiting lists through fewer patients requiring lab-based EDT assessment and that DES modelling is a useful tool in making this assessment. However, many questions remain about using the device in the real-world setting for this purpose. Future studies are needed to assess its sensitivity/specificity, test/retest variability, changes in referral patterns due to the device, useability, acceptability to patients and importantly, the consequences of screening errors. Our work, using only retrospective data and a DES model, shows that using the device as an ERG screening tool warrants further investigation due to the potential impact on both patients and clinical services.https://doi.org/10.1186/s12913-025-12551-wOphthalmologyElectrophysiologyElectoretinogramDES modellingRETevalTM
spellingShingle Steffen Bayer
Daniel Garillo
Marion Penn
Maria Chorozoglou
Sally Brailsford
Eloise Keeling
Fatima Shawkat
Perry Carter
Helena Lee
Jay E. Self
Could a hand-held, visual electrophysiology device theoretically reduce diagnostic waiting times for complex eye conditions in the NHS? A Discrete Event Simulation (DES) modelling study
BMC Health Services Research
Ophthalmology
Electrophysiology
Electoretinogram
DES modelling
RETevalTM
title Could a hand-held, visual electrophysiology device theoretically reduce diagnostic waiting times for complex eye conditions in the NHS? A Discrete Event Simulation (DES) modelling study
title_full Could a hand-held, visual electrophysiology device theoretically reduce diagnostic waiting times for complex eye conditions in the NHS? A Discrete Event Simulation (DES) modelling study
title_fullStr Could a hand-held, visual electrophysiology device theoretically reduce diagnostic waiting times for complex eye conditions in the NHS? A Discrete Event Simulation (DES) modelling study
title_full_unstemmed Could a hand-held, visual electrophysiology device theoretically reduce diagnostic waiting times for complex eye conditions in the NHS? A Discrete Event Simulation (DES) modelling study
title_short Could a hand-held, visual electrophysiology device theoretically reduce diagnostic waiting times for complex eye conditions in the NHS? A Discrete Event Simulation (DES) modelling study
title_sort could a hand held visual electrophysiology device theoretically reduce diagnostic waiting times for complex eye conditions in the nhs a discrete event simulation des modelling study
topic Ophthalmology
Electrophysiology
Electoretinogram
DES modelling
RETevalTM
url https://doi.org/10.1186/s12913-025-12551-w
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