Upper Gastrointestinal Tract Crohn's Disease
Crohn's disease may involve any site within the gastrointestinal tract. Usually pathology is present in the ileum and/or colon, but atypical presentations may occur with apparently 'isolated' involvement of the oropharynx, esophagus or gastroduodenum. If changes typical of Crohn'...
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
1990-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/1990/758048 |
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| _version_ | 1832551513231196160 |
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| author | Hugh J Freeman |
| author_facet | Hugh J Freeman |
| author_sort | Hugh J Freeman |
| collection | DOAJ |
| description | Crohn's disease may involve any site within the gastrointestinal
tract. Usually pathology is present in the ileum and/or colon, but atypical presentations
may occur with apparently 'isolated' involvement of the oropharynx, esophagus
or gastroduodenum. If changes typical of Crohn's disease are detected in the
upper gastrointestinal tract, then a careful assessment is required involving
radiographic, endoscopic and histologic studies to determine if pathology is present
in more distal intestine. In addition , microbiologic studies may be important to
exclude infectious causes, especially of granulomas. If these studies are negative,
prolonged follow-up may be required to establish a diagnosis of Crohn's disease.
Although upper gastrointestinal involvement is increasingly recognized as a significant
cause of morbidity in Crohn's disease, the treatment options are limited ,
largely anecdotal and need to be the subject of detailed epidemiologic investigation
and clinical trials. |
| format | Article |
| id | doaj-art-12d24582fa2d4af8845de8244d459e80 |
| institution | Kabale University |
| issn | 0835-7900 |
| language | English |
| publishDate | 1990-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology |
| spelling | doaj-art-12d24582fa2d4af8845de8244d459e802025-02-03T06:01:18ZengWileyCanadian Journal of Gastroenterology0835-79001990-01-0141263210.1155/1990/758048Upper Gastrointestinal Tract Crohn's DiseaseHugh J Freeman0Department of Medicine (Gastroenterology), University Hospital, CanadaCrohn's disease may involve any site within the gastrointestinal tract. Usually pathology is present in the ileum and/or colon, but atypical presentations may occur with apparently 'isolated' involvement of the oropharynx, esophagus or gastroduodenum. If changes typical of Crohn's disease are detected in the upper gastrointestinal tract, then a careful assessment is required involving radiographic, endoscopic and histologic studies to determine if pathology is present in more distal intestine. In addition , microbiologic studies may be important to exclude infectious causes, especially of granulomas. If these studies are negative, prolonged follow-up may be required to establish a diagnosis of Crohn's disease. Although upper gastrointestinal involvement is increasingly recognized as a significant cause of morbidity in Crohn's disease, the treatment options are limited , largely anecdotal and need to be the subject of detailed epidemiologic investigation and clinical trials.http://dx.doi.org/10.1155/1990/758048 |
| spellingShingle | Hugh J Freeman Upper Gastrointestinal Tract Crohn's Disease Canadian Journal of Gastroenterology |
| title | Upper Gastrointestinal Tract Crohn's Disease |
| title_full | Upper Gastrointestinal Tract Crohn's Disease |
| title_fullStr | Upper Gastrointestinal Tract Crohn's Disease |
| title_full_unstemmed | Upper Gastrointestinal Tract Crohn's Disease |
| title_short | Upper Gastrointestinal Tract Crohn's Disease |
| title_sort | upper gastrointestinal tract crohn s disease |
| url | http://dx.doi.org/10.1155/1990/758048 |
| work_keys_str_mv | AT hughjfreeman uppergastrointestinaltractcrohnsdisease |