Effects of Nd:Yag Laser on some virulence factor genes of Pseudomonas aeruginosa bacteria

The aim of this study was to assess effects of the 532nm Nd-yag laser on the genes of Tox A, Exo S, and Opr L, of Pseudomonas aeruginosa (P. aeruginosa) bacteria isolated from clinical (wounds, burns, otitis media) and environmental (water, soil) samples. Clinical samples were collected from patien...

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Main Authors: Aidah Abd Al-doori, Awatef Saber Jasem, Adnan F. AL-Azzawie
Format: Article
Language:English
Published: Tikrit University 2020-03-01
Series:Tikrit Journal of Pure Science
Subjects:
Online Access:https://tjpsj.org/index.php/tjps/article/view/240
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author Aidah Abd Al-doori
Awatef Saber Jasem
Adnan F. AL-Azzawie
author_facet Aidah Abd Al-doori
Awatef Saber Jasem
Adnan F. AL-Azzawie
author_sort Aidah Abd Al-doori
collection DOAJ
description The aim of this study was to assess effects of the 532nm Nd-yag laser on the genes of Tox A, Exo S, and Opr L, of Pseudomonas aeruginosa (P. aeruginosa) bacteria isolated from clinical (wounds, burns, otitis media) and environmental (water, soil) samples. Clinical samples were collected from patients coming to Saladdin General Hospital from wound, burns and middle ear infections while environmental samples were extracted from water and soil for Saladdin General Hospital . Bacterial samples irradiated by Nd-Yag laser with wavelength of 532 nm using energies (300mj,500mj) with (15 and 25 sec) and genomic DNA were extracted from all samples after the diagnosis of P. aeruginosa bacteria depending on the macroscopic and biochemical examination, then the PCR technique was performed. The results have shown an impact on P. aeruginosa bacteria of Nd-Yag laser by comparing PCR results of treated samples with control (unexposed) as loss of normal bands. This indicates that the laser had a genetic effect on the P. aeruginosa bacteria. We conclude that the laser induces genetic changes in P. aeruginosa's DNA so that lasers can be used in treatment and sterilization for clinical and environmental . The PCR technique could be used as a biomarker study to determine the biological effects of radiation on bacteria.
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institution Kabale University
issn 1813-1662
2415-1726
language English
publishDate 2020-03-01
publisher Tikrit University
record_format Article
series Tikrit Journal of Pure Science
spelling doaj-art-12ca7ee8c5aa4167afa93f1f5e1b6b6c2025-08-20T03:29:14ZengTikrit UniversityTikrit Journal of Pure Science1813-16622415-17262020-03-0125210.25130/tjps.v25i2.240Effects of Nd:Yag Laser on some virulence factor genes of Pseudomonas aeruginosa bacteriaAidah Abd Al-dooriAwatef Saber JasemAdnan F. AL-Azzawie The aim of this study was to assess effects of the 532nm Nd-yag laser on the genes of Tox A, Exo S, and Opr L, of Pseudomonas aeruginosa (P. aeruginosa) bacteria isolated from clinical (wounds, burns, otitis media) and environmental (water, soil) samples. Clinical samples were collected from patients coming to Saladdin General Hospital from wound, burns and middle ear infections while environmental samples were extracted from water and soil for Saladdin General Hospital . Bacterial samples irradiated by Nd-Yag laser with wavelength of 532 nm using energies (300mj,500mj) with (15 and 25 sec) and genomic DNA were extracted from all samples after the diagnosis of P. aeruginosa bacteria depending on the macroscopic and biochemical examination, then the PCR technique was performed. The results have shown an impact on P. aeruginosa bacteria of Nd-Yag laser by comparing PCR results of treated samples with control (unexposed) as loss of normal bands. This indicates that the laser had a genetic effect on the P. aeruginosa bacteria. We conclude that the laser induces genetic changes in P. aeruginosa's DNA so that lasers can be used in treatment and sterilization for clinical and environmental . The PCR technique could be used as a biomarker study to determine the biological effects of radiation on bacteria. https://tjpsj.org/index.php/tjps/article/view/240Laser Nd:YAGP.aeruginosavirulence factor
spellingShingle Aidah Abd Al-doori
Awatef Saber Jasem
Adnan F. AL-Azzawie
Effects of Nd:Yag Laser on some virulence factor genes of Pseudomonas aeruginosa bacteria
Tikrit Journal of Pure Science
Laser Nd:YAG
P.aeruginosa
virulence factor
title Effects of Nd:Yag Laser on some virulence factor genes of Pseudomonas aeruginosa bacteria
title_full Effects of Nd:Yag Laser on some virulence factor genes of Pseudomonas aeruginosa bacteria
title_fullStr Effects of Nd:Yag Laser on some virulence factor genes of Pseudomonas aeruginosa bacteria
title_full_unstemmed Effects of Nd:Yag Laser on some virulence factor genes of Pseudomonas aeruginosa bacteria
title_short Effects of Nd:Yag Laser on some virulence factor genes of Pseudomonas aeruginosa bacteria
title_sort effects of nd yag laser on some virulence factor genes of pseudomonas aeruginosa bacteria
topic Laser Nd:YAG
P.aeruginosa
virulence factor
url https://tjpsj.org/index.php/tjps/article/view/240
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AT awatefsaberjasem effectsofndyaglaseronsomevirulencefactorgenesofpseudomonasaeruginosabacteria
AT adnanfalazzawie effectsofndyaglaseronsomevirulencefactorgenesofpseudomonasaeruginosabacteria