Noninvasive Methods Unveil the Trophic Transmission of the Tapeworm Ligula intestinalis in Gull‐Billed Terns

ABSTRACT Recent developments in microscopic and molecular tools have allowed the implementation of new approaches for assessing parasitic infections in wildlife populations. This is particularly important for the noninvasive detection and quantification of endoparasites in live animals. Here, we com...

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Main Authors: Sofía Capasso, Manuel Parejo, José Manuel Reyes‐González, Juan G. Navedo, Ricardo Morán‐López, José A. Masero, Jorge S. Gutiérrez
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Ecology and Evolution
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Online Access:https://doi.org/10.1002/ece3.70564
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author Sofía Capasso
Manuel Parejo
José Manuel Reyes‐González
Juan G. Navedo
Ricardo Morán‐López
José A. Masero
Jorge S. Gutiérrez
author_facet Sofía Capasso
Manuel Parejo
José Manuel Reyes‐González
Juan G. Navedo
Ricardo Morán‐López
José A. Masero
Jorge S. Gutiérrez
author_sort Sofía Capasso
collection DOAJ
description ABSTRACT Recent developments in microscopic and molecular tools have allowed the implementation of new approaches for assessing parasitic infections in wildlife populations. This is particularly important for the noninvasive detection and quantification of endoparasites in live animals. Here, we combined copromicroscopic (Mini‐FLOTAC) and molecular (qPCR) techniques to detect the infection of the macroparasite Ligula intestinalis (Cestoda, Pseudophyllidea) in fresh droppings of Gull‐billed Terns Gelochelidon nilotica (Charadriiformes, Laridae) breeding in southwestern Spain. Additionally, we sequenced the cytochrome b gene in parasite isolates from Gull‐billed Terns (definitive host) and Common Bleak Alburnus alburnus (second intermediate host) sampled around tern colonies to explore potential genetic differences between the isolates. The qPCR test showed a higher prevalence (18%; in 13/73 samples) than Mini‐FLOTAC (9%; in 8/88 samples), indicating that qPCR was more sensitive for diagnostic purposes than fecal flotation alone. Although the agreement between both techniques was substantial (84.2%) mainly due to the large number of uninfected samples, only Mini‐FLOTAC allowed us to quantify parasite shedding. When combining techniques, the prevalence of infection did not differ between adults and chicks, suggesting frequent trophic transmission from parents to their offspring via food provisioning. Phylogenetic analyses identified four haplotypes in the isolates from Gull‐billed Terns and Bleak, all of which were placed within a European clade composed of tapeworms recovered exclusively from phylogenetically derived cyprinid fish. This, combined with the short lifespan of mature tapeworms, suggests that Gull‐billed Terns became infected after consuming infected fish around their breeding colonies rather than on their West African wintering grounds. Altogether, our results represent the first record of L. intestinalis in Gull‐billed Terns and the first molecular characterization of the parasite in the Iberian Peninsula. This integrative coprodiagnostic protocol can be applied to other host–parasite systems, allowing researchers to study helminth infections in wild populations using a noninvasive approach.
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spelling doaj-art-12c0bfa4aed94f9ebd813b06c2365a502025-08-20T01:58:19ZengWileyEcology and Evolution2045-77582024-11-011411n/an/a10.1002/ece3.70564Noninvasive Methods Unveil the Trophic Transmission of the Tapeworm Ligula intestinalis in Gull‐Billed TernsSofía Capasso0Manuel Parejo1José Manuel Reyes‐González2Juan G. Navedo3Ricardo Morán‐López4José A. Masero5Jorge S. Gutiérrez6Departamento de Anatomía, Biología Celular y Zoología, Facultad de Ciencias Universidad de Extremadura Badajoz SpainDepartamento de Anatomía, Biología Celular y Zoología, Facultad de Ciencias Universidad de Extremadura Badajoz SpainDepartamento de Anatomía, Biología Celular y Zoología, Facultad de Ciencias Universidad de Extremadura Badajoz SpainDepartamento de Anatomía, Biología Celular y Zoología, Facultad de Ciencias Universidad de Extremadura Badajoz SpainDepartamento de Anatomía, Biología Celular y Zoología, Facultad de Ciencias Universidad de Extremadura Badajoz SpainDepartamento de Anatomía, Biología Celular y Zoología, Facultad de Ciencias Universidad de Extremadura Badajoz SpainDepartamento de Anatomía, Biología Celular y Zoología, Facultad de Ciencias Universidad de Extremadura Badajoz SpainABSTRACT Recent developments in microscopic and molecular tools have allowed the implementation of new approaches for assessing parasitic infections in wildlife populations. This is particularly important for the noninvasive detection and quantification of endoparasites in live animals. Here, we combined copromicroscopic (Mini‐FLOTAC) and molecular (qPCR) techniques to detect the infection of the macroparasite Ligula intestinalis (Cestoda, Pseudophyllidea) in fresh droppings of Gull‐billed Terns Gelochelidon nilotica (Charadriiformes, Laridae) breeding in southwestern Spain. Additionally, we sequenced the cytochrome b gene in parasite isolates from Gull‐billed Terns (definitive host) and Common Bleak Alburnus alburnus (second intermediate host) sampled around tern colonies to explore potential genetic differences between the isolates. The qPCR test showed a higher prevalence (18%; in 13/73 samples) than Mini‐FLOTAC (9%; in 8/88 samples), indicating that qPCR was more sensitive for diagnostic purposes than fecal flotation alone. Although the agreement between both techniques was substantial (84.2%) mainly due to the large number of uninfected samples, only Mini‐FLOTAC allowed us to quantify parasite shedding. When combining techniques, the prevalence of infection did not differ between adults and chicks, suggesting frequent trophic transmission from parents to their offspring via food provisioning. Phylogenetic analyses identified four haplotypes in the isolates from Gull‐billed Terns and Bleak, all of which were placed within a European clade composed of tapeworms recovered exclusively from phylogenetically derived cyprinid fish. This, combined with the short lifespan of mature tapeworms, suggests that Gull‐billed Terns became infected after consuming infected fish around their breeding colonies rather than on their West African wintering grounds. Altogether, our results represent the first record of L. intestinalis in Gull‐billed Terns and the first molecular characterization of the parasite in the Iberian Peninsula. This integrative coprodiagnostic protocol can be applied to other host–parasite systems, allowing researchers to study helminth infections in wild populations using a noninvasive approach.https://doi.org/10.1002/ece3.70564Cestodafecal egg countfish‐eating birdshelminthsmini‐FLOTACreal‐time qPCR
spellingShingle Sofía Capasso
Manuel Parejo
José Manuel Reyes‐González
Juan G. Navedo
Ricardo Morán‐López
José A. Masero
Jorge S. Gutiérrez
Noninvasive Methods Unveil the Trophic Transmission of the Tapeworm Ligula intestinalis in Gull‐Billed Terns
Ecology and Evolution
Cestoda
fecal egg count
fish‐eating birds
helminths
mini‐FLOTAC
real‐time qPCR
title Noninvasive Methods Unveil the Trophic Transmission of the Tapeworm Ligula intestinalis in Gull‐Billed Terns
title_full Noninvasive Methods Unveil the Trophic Transmission of the Tapeworm Ligula intestinalis in Gull‐Billed Terns
title_fullStr Noninvasive Methods Unveil the Trophic Transmission of the Tapeworm Ligula intestinalis in Gull‐Billed Terns
title_full_unstemmed Noninvasive Methods Unveil the Trophic Transmission of the Tapeworm Ligula intestinalis in Gull‐Billed Terns
title_short Noninvasive Methods Unveil the Trophic Transmission of the Tapeworm Ligula intestinalis in Gull‐Billed Terns
title_sort noninvasive methods unveil the trophic transmission of the tapeworm ligula intestinalis in gull billed terns
topic Cestoda
fecal egg count
fish‐eating birds
helminths
mini‐FLOTAC
real‐time qPCR
url https://doi.org/10.1002/ece3.70564
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