Synthesis of Novel Antibacterial Agents: 1-(2', 4'-Dihydroxy-5'-chlorophenyl)-3-arylpropane-1, 3-Diones
1-(2', 4'-Dihydroxy-5'-chlorophenyl)-3-arylpropane-1, 3-diones(3a-h) have been synthesized by a simple and convenient method employing Baker-Venkatraman transformation on 2-aroyloxy-4-hydroxy-5-chloroacetophenones (2a-h) with NaOH in dimethylsuphoxide regardless of pyridine. The struc...
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| Format: | Article |
| Language: | English |
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Wiley
2009-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2009/693495 |
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| author | J. I. Sheikh V. N. Ingle H. D. Juneja |
| author_facet | J. I. Sheikh V. N. Ingle H. D. Juneja |
| author_sort | J. I. Sheikh |
| collection | DOAJ |
| description | 1-(2', 4'-Dihydroxy-5'-chlorophenyl)-3-arylpropane-1, 3-diones(3a-h) have been synthesized by a simple and convenient method employing Baker-Venkatraman transformation on 2-aroyloxy-4-hydroxy-5-chloroacetophenones (2a-h) with NaOH in dimethylsuphoxide regardless of pyridine. The structures of the synthesized compounds have been assigned on the basis of elemental and spectral analyses (IR, 1HNMR, 13C NMR, Mass). The synthesized compounds were evaluated for the antibacterial efficacy against gram negative and gram positive bacteria. |
| format | Article |
| id | doaj-art-12bd1aaf25ba483caf88e30aa46d2ed6 |
| institution | OA Journals |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-12bd1aaf25ba483caf88e30aa46d2ed62025-08-20T02:02:12ZengWileyE-Journal of Chemistry0973-49452090-98102009-01-016370571210.1155/2009/693495Synthesis of Novel Antibacterial Agents: 1-(2', 4'-Dihydroxy-5'-chlorophenyl)-3-arylpropane-1, 3-DionesJ. I. Sheikh0V. N. Ingle1H. D. Juneja2Organic Chemistry Research Laboratory, Department of Chemistry, RTM Nagpur University, Nagpur-440 033, IndiaOrganic Chemistry Research Laboratory, Department of Chemistry, RTM Nagpur University, Nagpur-440 033, IndiaOrganic Chemistry Research Laboratory, Department of Chemistry, RTM Nagpur University, Nagpur-440 033, India1-(2', 4'-Dihydroxy-5'-chlorophenyl)-3-arylpropane-1, 3-diones(3a-h) have been synthesized by a simple and convenient method employing Baker-Venkatraman transformation on 2-aroyloxy-4-hydroxy-5-chloroacetophenones (2a-h) with NaOH in dimethylsuphoxide regardless of pyridine. The structures of the synthesized compounds have been assigned on the basis of elemental and spectral analyses (IR, 1HNMR, 13C NMR, Mass). The synthesized compounds were evaluated for the antibacterial efficacy against gram negative and gram positive bacteria.http://dx.doi.org/10.1155/2009/693495 |
| spellingShingle | J. I. Sheikh V. N. Ingle H. D. Juneja Synthesis of Novel Antibacterial Agents: 1-(2', 4'-Dihydroxy-5'-chlorophenyl)-3-arylpropane-1, 3-Diones E-Journal of Chemistry |
| title | Synthesis of Novel Antibacterial Agents: 1-(2', 4'-Dihydroxy-5'-chlorophenyl)-3-arylpropane-1, 3-Diones |
| title_full | Synthesis of Novel Antibacterial Agents: 1-(2', 4'-Dihydroxy-5'-chlorophenyl)-3-arylpropane-1, 3-Diones |
| title_fullStr | Synthesis of Novel Antibacterial Agents: 1-(2', 4'-Dihydroxy-5'-chlorophenyl)-3-arylpropane-1, 3-Diones |
| title_full_unstemmed | Synthesis of Novel Antibacterial Agents: 1-(2', 4'-Dihydroxy-5'-chlorophenyl)-3-arylpropane-1, 3-Diones |
| title_short | Synthesis of Novel Antibacterial Agents: 1-(2', 4'-Dihydroxy-5'-chlorophenyl)-3-arylpropane-1, 3-Diones |
| title_sort | synthesis of novel antibacterial agents 1 2 4 dihydroxy 5 chlorophenyl 3 arylpropane 1 3 diones |
| url | http://dx.doi.org/10.1155/2009/693495 |
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