Unraveling the mystery: How autophagy deficiency in dopaminergic neurons drives human Parkinson’s disease
Abstract Alpha-synuclein (α-synuclein), a key component of Lewy body pathology, is a classical hallmark of Parkinson’s disease. In previous studies, our group has examined dopaminergic neuron-specific Atg7 autophagy-deficient mice, observing α-synuclein aggregation in vivo. This pathological process...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-07-01
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| Series: | Molecular Brain |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13041-025-01235-5 |
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