DEVELOPMENT OF PRODUCING SOFT MEDICINAL FORMS CONTAINING SOLID DISPERSION
The technology of obtaining samples of ointments of nifedipine on the emulsion and hydrophilic bases using the method of solid dispersions is developed. The quality of the obtained soft medicinal forms was evaluated. The effectiveness of the proposed technology for the preparation of nifedipine oint...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
2019-01-01
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| Series: | Разработка и регистрация лекарственных средств |
| Subjects: | |
| Online Access: | https://www.pharmjournal.ru/jour/article/view/542 |
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| Summary: | The technology of obtaining samples of ointments of nifedipine on the emulsion and hydrophilic bases using the method of solid dispersions is developed. The quality of the obtained soft medicinal forms was evaluated. The effectiveness of the proposed technology for the preparation of nifedipine ointments has been proved, which makes it possible to increase the pharmaceutical availability of the water-soluble test substance, providing better release by increasing its solubility and dissolution rate. |
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| ISSN: | 2305-2066 2658-5049 |