Galectin-3 secreted by triple-negative breast cancer cells regulates T cell function

Galectin-3 secreted by triple-negative breast cancer cells regulates T cell function

Triple-negative breast cancer (TNBC) is an aggressive subtype that accounts for 10-15 % of breast cancer. Current treatment of high-risk early-stage TNBC includes neoadjuvant chemo-immune therapy. However, the substantial variation in immune response prompts an urgent need for new immune-targeting a...

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Bibliographic Details
Main Authors: Annat Raiter, Yael Barhum, Julia Lipovetsky, Chen Menachem, Sharona Elgavish, Shmuel Ruppo, Yehudit Birger, Shai Izraeli, Orna Steinberg-Shemer, Rinat Yerushalmi
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Triple negative breast cancer
Galectin-3
T exhausted cells
Oxidative phosphorylation
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558624001581
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