Quality of Life and Age-Related Predictor Symptoms in Breast Cancer Survivors Undergoing Hormone Therapy: A Study from the Northern Region of Morocco
Objective: The aim of this study was to assess the health-related quality of life (HRQoL) of breast cancer (BC) survivors during adjuvant hormone therapy (AHT) as a function of age and to identify predictor symptoms. Materials and Methods: The study was based on a cross-sectional survey of 216 BC s...
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| Format: | Article |
| Language: | English |
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Galenos Publishing House
2025-04-01
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| Series: | European Journal of Breast Health |
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| Online Access: | https://www.eurjbreasthealth.com/articles/quality-of-life-and-age-related-predictor-symptoms-in-breast-cancer-survivors-undergoing-hormone-therapy-a-study-from-the-northern-region-of-morocco/doi/ejbh.galenos.2025.2024-5-4 |
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| author | Fadoua El Battioui Abdelouahid Louazi Noura Boukil Zohra Ben Allal Rajae Alloudane Said Barrijal |
| author_facet | Fadoua El Battioui Abdelouahid Louazi Noura Boukil Zohra Ben Allal Rajae Alloudane Said Barrijal |
| author_sort | Fadoua El Battioui |
| collection | DOAJ |
| description | Objective: The aim of this study was to assess the health-related quality of life (HRQoL) of breast cancer (BC) survivors during adjuvant hormone therapy (AHT) as a function of age and to identify predictor symptoms.
Materials and Methods: The study was based on a cross-sectional survey of 216 BC survivors undergoing AHT, in the Northern Region of Morocco. HRQoL was assessed using a validated HRQoL questionnaire, the Functional Assessment of Cancer Treatment (FACT-ES). Multiple linear regression analysis was used to identify predictor symptoms for the subscales of the FACT-ES.
Results: Younger women (<45 years) had lower scores on the emotional well-being subscale (p = 0.021). Irritability (b: -0.786; p = 0.001) and mood swings (b: -0.835; p = 0.031) were the strongest negative predictors of emotional quality of life. In both age groups, items related to social support had a positive effect on survivors’ social HRQoL (p<0.05).
Conclusion: BC survivors’ HRQoL during AHT differed by age group. Emotional problems negatively influenced HRQoL in younger women. Knowledge of the symptoms that predict HRQoL in BC survivors may help clinicians develop personalized interventions. |
| format | Article |
| id | doaj-art-12906390892e4d12a1d9ca5409cd45a9 |
| institution | Kabale University |
| issn | 2587-0831 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | European Journal of Breast Health |
| spelling | doaj-art-12906390892e4d12a1d9ca5409cd45a92025-08-20T03:43:54ZengGalenos Publishing HouseEuropean Journal of Breast Health2587-08312025-04-0121211512110.4274/ejbh.galenos.2025.2024-5-4Quality of Life and Age-Related Predictor Symptoms in Breast Cancer Survivors Undergoing Hormone Therapy: A Study from the Northern Region of MoroccoFadoua El Battioui0https://orcid.org/0000-0002-5069-2899Abdelouahid Louazi1https://orcid.org/0000-0001-7802-0376Noura Boukil2https://orcid.org/0009-0003-1478-5494Zohra Ben Allal3https://orcid.org/0009-0002-0417-7164Rajae Alloudane4https://orcid.org/0009-0003-0718-0569Said Barrijal5https://orcid.org/0000-0002-7616-8331Laboratory of Biotechnology, Genomic and Bioinformatics, Faculty of Science and Techniques,Tangier, Abdelmalek Essaâdi University, Tetouan, MoroccoInstitute of Nursing,Tetouan, MoroccoDepartment of Biology and Health, Faculty of Sciences, Abdelmalek Essâadi University, Tétouan, MoroccoFaculty of medicine and pharmacy, Abdelmalek Essaadi University, Tetouan, MoroccoLaboratory of Biotechnology, Genomic and Bioinformatics, Faculty of Science and Techniques,Tangier, Abdelmalek Essaâdi University, Tetouan, MoroccoLaboratory of Biotechnology, Genomic and Bioinformatics, Faculty of Science and Techniques,Tangier, Abdelmalek Essaâdi University, Tetouan, MoroccoObjective: The aim of this study was to assess the health-related quality of life (HRQoL) of breast cancer (BC) survivors during adjuvant hormone therapy (AHT) as a function of age and to identify predictor symptoms. Materials and Methods: The study was based on a cross-sectional survey of 216 BC survivors undergoing AHT, in the Northern Region of Morocco. HRQoL was assessed using a validated HRQoL questionnaire, the Functional Assessment of Cancer Treatment (FACT-ES). Multiple linear regression analysis was used to identify predictor symptoms for the subscales of the FACT-ES. Results: Younger women (<45 years) had lower scores on the emotional well-being subscale (p = 0.021). Irritability (b: -0.786; p = 0.001) and mood swings (b: -0.835; p = 0.031) were the strongest negative predictors of emotional quality of life. In both age groups, items related to social support had a positive effect on survivors’ social HRQoL (p<0.05). Conclusion: BC survivors’ HRQoL during AHT differed by age group. Emotional problems negatively influenced HRQoL in younger women. Knowledge of the symptoms that predict HRQoL in BC survivors may help clinicians develop personalized interventions.https://www.eurjbreasthealth.com/articles/quality-of-life-and-age-related-predictor-symptoms-in-breast-cancer-survivors-undergoing-hormone-therapy-a-study-from-the-northern-region-of-morocco/doi/ejbh.galenos.2025.2024-5-4agebreast cancerhormone therapyquality of lifepredictor symptomssurvivors |
| spellingShingle | Fadoua El Battioui Abdelouahid Louazi Noura Boukil Zohra Ben Allal Rajae Alloudane Said Barrijal Quality of Life and Age-Related Predictor Symptoms in Breast Cancer Survivors Undergoing Hormone Therapy: A Study from the Northern Region of Morocco European Journal of Breast Health age breast cancer hormone therapy quality of life predictor symptoms survivors |
| title | Quality of Life and Age-Related Predictor Symptoms in Breast Cancer Survivors Undergoing Hormone Therapy: A Study from the Northern Region of Morocco |
| title_full | Quality of Life and Age-Related Predictor Symptoms in Breast Cancer Survivors Undergoing Hormone Therapy: A Study from the Northern Region of Morocco |
| title_fullStr | Quality of Life and Age-Related Predictor Symptoms in Breast Cancer Survivors Undergoing Hormone Therapy: A Study from the Northern Region of Morocco |
| title_full_unstemmed | Quality of Life and Age-Related Predictor Symptoms in Breast Cancer Survivors Undergoing Hormone Therapy: A Study from the Northern Region of Morocco |
| title_short | Quality of Life and Age-Related Predictor Symptoms in Breast Cancer Survivors Undergoing Hormone Therapy: A Study from the Northern Region of Morocco |
| title_sort | quality of life and age related predictor symptoms in breast cancer survivors undergoing hormone therapy a study from the northern region of morocco |
| topic | age breast cancer hormone therapy quality of life predictor symptoms survivors |
| url | https://www.eurjbreasthealth.com/articles/quality-of-life-and-age-related-predictor-symptoms-in-breast-cancer-survivors-undergoing-hormone-therapy-a-study-from-the-northern-region-of-morocco/doi/ejbh.galenos.2025.2024-5-4 |
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