FLAIR vascular hyperintensity is associated with functional outcome in patients with ischemic stroke receiving endovascular treatment: a meta-analysis

BackgroundFluid-attenuated inversion recovery (FLAIR) vascular hyperintensity (FVH) might be useful for predicting and functional outcome in ischemic stroke patients after endovascular thrombectomy (EVT), but its clinical benefit remains controversial. Thus, this study aimed to evaluate the associat...

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Main Authors: Chunyan Wang, Chuanliu Wang, Yongjun Ni
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Neurology
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Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2024.1497504/full
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author Chunyan Wang
Chuanliu Wang
Yongjun Ni
author_facet Chunyan Wang
Chuanliu Wang
Yongjun Ni
author_sort Chunyan Wang
collection DOAJ
description BackgroundFluid-attenuated inversion recovery (FLAIR) vascular hyperintensity (FVH) might be useful for predicting and functional outcome in ischemic stroke patients after endovascular thrombectomy (EVT), but its clinical benefit remains controversial. Thus, this study aimed to evaluate the association of FVH on prognosis in ischemic stroke patients who received EVT.MethodsPubMed, Embase, Cochrane Library, Web of Science, and Wanfang databases were searched for potentially eligible studies published up to March 2024. Pooled standard mean difference (SMD), risk ratios (RR) with 95% confidence intervals (CI) were employed to assess the association of FVH on prognosis in ischemic stroke patients who received EVT. All statistical analyses were conducted using STATA 12.0 software.ResultsA total of 10 studies were included in our study. The results indicated that higher FVH score were associated with better prognosis (SMD: 0.80, 95% CI 0.63–0.97). Moreover, the presence of FVH was significant associated with better functional outcome in ischemic stroke patients who received EVT (RR: 0.68, 95% CI, 0.58–0.79).ConclusionThe current meta-analysis suggests that FVH is related the prognosis of ischemic stroke patients after EVT.
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spelling doaj-art-128c211c1b6e4c8d86f3ea53762151e32025-08-20T02:14:20ZengFrontiers Media S.A.Frontiers in Neurology1664-22952024-11-011510.3389/fneur.2024.14975041497504FLAIR vascular hyperintensity is associated with functional outcome in patients with ischemic stroke receiving endovascular treatment: a meta-analysisChunyan Wang0Chuanliu Wang1Yongjun Ni2Department of Radiology, The Quzhou Affiliated Hospital of Wenzhou Medical University, (Quzhou People’s Hospital), Quzhou, ChinaDepartment of Neurology, The Quzhou Affiliated Hospital of Wenzhou Medical University, (Quzhou People’s Hospital), Quzhou, ChinaDepartment of Radiology, Jiaxing Maternity and Child Health Care Hospital, Jiaxing, ChinaBackgroundFluid-attenuated inversion recovery (FLAIR) vascular hyperintensity (FVH) might be useful for predicting and functional outcome in ischemic stroke patients after endovascular thrombectomy (EVT), but its clinical benefit remains controversial. Thus, this study aimed to evaluate the association of FVH on prognosis in ischemic stroke patients who received EVT.MethodsPubMed, Embase, Cochrane Library, Web of Science, and Wanfang databases were searched for potentially eligible studies published up to March 2024. Pooled standard mean difference (SMD), risk ratios (RR) with 95% confidence intervals (CI) were employed to assess the association of FVH on prognosis in ischemic stroke patients who received EVT. All statistical analyses were conducted using STATA 12.0 software.ResultsA total of 10 studies were included in our study. The results indicated that higher FVH score were associated with better prognosis (SMD: 0.80, 95% CI 0.63–0.97). Moreover, the presence of FVH was significant associated with better functional outcome in ischemic stroke patients who received EVT (RR: 0.68, 95% CI, 0.58–0.79).ConclusionThe current meta-analysis suggests that FVH is related the prognosis of ischemic stroke patients after EVT.https://www.frontiersin.org/articles/10.3389/fneur.2024.1497504/fullvascular hyperintensityFLAIRischemic strokeendovascular thrombectomymeta-analysis
spellingShingle Chunyan Wang
Chuanliu Wang
Yongjun Ni
FLAIR vascular hyperintensity is associated with functional outcome in patients with ischemic stroke receiving endovascular treatment: a meta-analysis
Frontiers in Neurology
vascular hyperintensity
FLAIR
ischemic stroke
endovascular thrombectomy
meta-analysis
title FLAIR vascular hyperintensity is associated with functional outcome in patients with ischemic stroke receiving endovascular treatment: a meta-analysis
title_full FLAIR vascular hyperintensity is associated with functional outcome in patients with ischemic stroke receiving endovascular treatment: a meta-analysis
title_fullStr FLAIR vascular hyperintensity is associated with functional outcome in patients with ischemic stroke receiving endovascular treatment: a meta-analysis
title_full_unstemmed FLAIR vascular hyperintensity is associated with functional outcome in patients with ischemic stroke receiving endovascular treatment: a meta-analysis
title_short FLAIR vascular hyperintensity is associated with functional outcome in patients with ischemic stroke receiving endovascular treatment: a meta-analysis
title_sort flair vascular hyperintensity is associated with functional outcome in patients with ischemic stroke receiving endovascular treatment a meta analysis
topic vascular hyperintensity
FLAIR
ischemic stroke
endovascular thrombectomy
meta-analysis
url https://www.frontiersin.org/articles/10.3389/fneur.2024.1497504/full
work_keys_str_mv AT chunyanwang flairvascularhyperintensityisassociatedwithfunctionaloutcomeinpatientswithischemicstrokereceivingendovasculartreatmentametaanalysis
AT chuanliuwang flairvascularhyperintensityisassociatedwithfunctionaloutcomeinpatientswithischemicstrokereceivingendovasculartreatmentametaanalysis
AT yongjunni flairvascularhyperintensityisassociatedwithfunctionaloutcomeinpatientswithischemicstrokereceivingendovasculartreatmentametaanalysis