A 15-year-old Girl with a Lateral Neck Mass Turning Out to Be Papillary Thyroid Carcinoma - Lateral Ectopic Papillary Thyroid Carcinoma or Lymph Node Metastasis?
Lateral neck lesions in children are common and involve various infectious or inflammatory etiologies, as well as embryological remnants such as branchial cleft cysts. Although unusual, ectopic thyroid tissue may also present as a lateral neck mass. Here, we present an unusual case of a 15-year-old...
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Galenos Yayincilik
2025-06-01
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| Series: | JCRPE |
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| Online Access: | https://www.jcrpe.org/articles/a-15-year-old-girl-with-a-lateral-neck-mass-turning-out-to-be-papillary-thyroid-carcinoma-lateral-ectopic-papillary-thyroid-carcinoma-or-lymph-node-metastasis/doi/jcrpe.galenos.2023.2023-4-6 |
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| author | Marijke E.B. Kremer A.S. Paul van Trotsenburg Anton F. Engelsman Esther Edelenbos Arantza Farina-Sarasqueta Joost van Schuppen José C.C. Koppes Joep P.M Derikx Christiaan F. Mooij |
| author_facet | Marijke E.B. Kremer A.S. Paul van Trotsenburg Anton F. Engelsman Esther Edelenbos Arantza Farina-Sarasqueta Joost van Schuppen José C.C. Koppes Joep P.M Derikx Christiaan F. Mooij |
| author_sort | Marijke E.B. Kremer |
| collection | DOAJ |
| description | Lateral neck lesions in children are common and involve various infectious or inflammatory etiologies, as well as embryological remnants such as branchial cleft cysts. Although unusual, ectopic thyroid tissue may also present as a lateral neck mass. Here, we present an unusual case of a 15-year-old girl treated for an asymptomatic lateral neck mass that, after surgical removal, was found to be papillary thyroid carcinoma (PTC). However, after removal of the thyroid gland, no primary thyroid tumor was found. The question arose whether the lateral neck lesion was a lymph node metastasis without identifiable primary tumor by histological evaluation, or rather malignant degeneration of ectopic thyroid tissue. Total thyroidectomy was performed with postoperative adjuvant radioactive iodine ablation. Even though PTC in a lateral neck mass without a primary thyroid tumor has been described previously, pediatric cases have not been reported. In this report we share our experience on diagnosis, treatment and follow-up, and review the existing literature. |
| format | Article |
| id | doaj-art-128b6210f24946bbbdb9fcb7dd2996d4 |
| institution | Kabale University |
| issn | 1308-5727 1308-5735 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Galenos Yayincilik |
| record_format | Article |
| series | JCRPE |
| spelling | doaj-art-128b6210f24946bbbdb9fcb7dd2996d42025-08-20T03:46:41ZengGalenos YayincilikJCRPE1308-57271308-57352025-06-0117223123610.4274/jcrpe.galenos.2023.2023-4-6A 15-year-old Girl with a Lateral Neck Mass Turning Out to Be Papillary Thyroid Carcinoma - Lateral Ectopic Papillary Thyroid Carcinoma or Lymph Node Metastasis?Marijke E.B. Kremer0https://orcid.org/0000-0002-6032-0562A.S. Paul van Trotsenburg1https://orcid.org/0000-0002-9677-7441Anton F. Engelsman2https://orcid.org/0000-0003-4943-8882Esther Edelenbos3https://orcid.org/0000-0002-9226-856XArantza Farina-Sarasqueta4https://orcid.org/0000-0002-4307-1568Joost van Schuppen5https://orcid.org/0000-0003-4982-6615José C.C. Koppes6https://orcid.org/0009-0001-3527-6221Joep P.M Derikx7https://orcid.org/0000-0003-0694-7679Christiaan F. Mooij8https://orcid.org/0000-0001-7977-6271Department of Pediatric Surgery, Emma Children’s Hospital, Amsterdam University Medical Centers, University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The NetherlandsDepartment of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam University Medical Centers, University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The NetherlandsDepartment of Surgery, Amsterdam University Medical Centers, University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The NetherlandsDepartment of Pediatric Oncology, Emma Children’s Hospital, Amsterdam University Medical Centers, University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The NetherlandsDepartment of Pathology, Amsterdam University Medical Centers, University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The NetherlandsDepartment of Radiology and Nuclear Medicine, Amsterdam University Medical Centers, University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The NetherlandsDepartment of Radiology and Nuclear Medicine, Amsterdam University Medical Centers, University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The NetherlandsDepartment of Pediatric Surgery, Emma Children’s Hospital, Amsterdam University Medical Centers, University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The NetherlandsDepartment of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam University Medical Centers, University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The NetherlandsLateral neck lesions in children are common and involve various infectious or inflammatory etiologies, as well as embryological remnants such as branchial cleft cysts. Although unusual, ectopic thyroid tissue may also present as a lateral neck mass. Here, we present an unusual case of a 15-year-old girl treated for an asymptomatic lateral neck mass that, after surgical removal, was found to be papillary thyroid carcinoma (PTC). However, after removal of the thyroid gland, no primary thyroid tumor was found. The question arose whether the lateral neck lesion was a lymph node metastasis without identifiable primary tumor by histological evaluation, or rather malignant degeneration of ectopic thyroid tissue. Total thyroidectomy was performed with postoperative adjuvant radioactive iodine ablation. Even though PTC in a lateral neck mass without a primary thyroid tumor has been described previously, pediatric cases have not been reported. In this report we share our experience on diagnosis, treatment and follow-up, and review the existing literature.https://www.jcrpe.org/articles/a-15-year-old-girl-with-a-lateral-neck-mass-turning-out-to-be-papillary-thyroid-carcinoma-lateral-ectopic-papillary-thyroid-carcinoma-or-lymph-node-metastasis/doi/jcrpe.galenos.2023.2023-4-6thyroid dysgenesisthyroid papillary carcinomacervical neck mass |
| spellingShingle | Marijke E.B. Kremer A.S. Paul van Trotsenburg Anton F. Engelsman Esther Edelenbos Arantza Farina-Sarasqueta Joost van Schuppen José C.C. Koppes Joep P.M Derikx Christiaan F. Mooij A 15-year-old Girl with a Lateral Neck Mass Turning Out to Be Papillary Thyroid Carcinoma - Lateral Ectopic Papillary Thyroid Carcinoma or Lymph Node Metastasis? JCRPE thyroid dysgenesis thyroid papillary carcinoma cervical neck mass |
| title | A 15-year-old Girl with a Lateral Neck Mass Turning Out to Be Papillary Thyroid Carcinoma - Lateral Ectopic Papillary Thyroid Carcinoma or Lymph Node Metastasis? |
| title_full | A 15-year-old Girl with a Lateral Neck Mass Turning Out to Be Papillary Thyroid Carcinoma - Lateral Ectopic Papillary Thyroid Carcinoma or Lymph Node Metastasis? |
| title_fullStr | A 15-year-old Girl with a Lateral Neck Mass Turning Out to Be Papillary Thyroid Carcinoma - Lateral Ectopic Papillary Thyroid Carcinoma or Lymph Node Metastasis? |
| title_full_unstemmed | A 15-year-old Girl with a Lateral Neck Mass Turning Out to Be Papillary Thyroid Carcinoma - Lateral Ectopic Papillary Thyroid Carcinoma or Lymph Node Metastasis? |
| title_short | A 15-year-old Girl with a Lateral Neck Mass Turning Out to Be Papillary Thyroid Carcinoma - Lateral Ectopic Papillary Thyroid Carcinoma or Lymph Node Metastasis? |
| title_sort | 15 year old girl with a lateral neck mass turning out to be papillary thyroid carcinoma lateral ectopic papillary thyroid carcinoma or lymph node metastasis |
| topic | thyroid dysgenesis thyroid papillary carcinoma cervical neck mass |
| url | https://www.jcrpe.org/articles/a-15-year-old-girl-with-a-lateral-neck-mass-turning-out-to-be-papillary-thyroid-carcinoma-lateral-ectopic-papillary-thyroid-carcinoma-or-lymph-node-metastasis/doi/jcrpe.galenos.2023.2023-4-6 |
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