A Case of Complete Remission from Advanced Gastric Adenocarcinoma with Synchronous Liver Metastasis in Response to EOX Chemotherapy
Gastric cancer is a malignant tumor with a high degree of malignancy. Multiple liver metastases from gastric cancer (LMGCs) are common. However, the treatment of LMGCs is very difficult. It is rare to achieve complete remission (CR) and long-term survival after treatment. We present the case of a pa...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Gastrointestinal Medicine |
| Online Access: | http://dx.doi.org/10.1155/2018/3954260 |
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| author | Zhi-jun Yan Jia-xin Wang You-yi Liu Zhen-hui Li Li-juan Zhang Ping Gan Xiao Han Li-kun Luan You-guo Dai |
| author_facet | Zhi-jun Yan Jia-xin Wang You-yi Liu Zhen-hui Li Li-juan Zhang Ping Gan Xiao Han Li-kun Luan You-guo Dai |
| author_sort | Zhi-jun Yan |
| collection | DOAJ |
| description | Gastric cancer is a malignant tumor with a high degree of malignancy. Multiple liver metastases from gastric cancer (LMGCs) are common. However, the treatment of LMGCs is very difficult. It is rare to achieve complete remission (CR) and long-term survival after treatment. We present the case of a patient with gastric adenocarcinoma and multiple liver metastases who showed CR for more than 33 months after perioperative EOX (epirubicin, oxaliplatin, and capecitabine) combination chemotherapy with radical distal gastrectomy and resection of liver metastases. The patient is still in follow-up without tumor recurrence. These findings suggest that LMGC does not necessarily mean a poor prognosis; preoperative chemotherapy combined with surgery may be a good treatment option for LMGC in selected patients. Further studies are needed to support this treatment approach. |
| format | Article |
| id | doaj-art-127f3ff214974a7bbb2f15849954790f |
| institution | Kabale University |
| issn | 2090-6528 2090-6536 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Gastrointestinal Medicine |
| spelling | doaj-art-127f3ff214974a7bbb2f15849954790f2025-08-20T03:55:44ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362018-01-01201810.1155/2018/39542603954260A Case of Complete Remission from Advanced Gastric Adenocarcinoma with Synchronous Liver Metastasis in Response to EOX ChemotherapyZhi-jun Yan0Jia-xin Wang1You-yi Liu2Zhen-hui Li3Li-juan Zhang4Ping Gan5Xiao Han6Li-kun Luan7You-guo Dai8Department of Abdominal Surgery, Third Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650118, ChinaDepartment of Abdominal Surgery, Third Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650118, ChinaDepartment of Abdominal Surgery, Third Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650118, ChinaDepartment of Radiology, Third Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650118, ChinaDepartment of Pathology, Third Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650118, ChinaDepartment of Abdominal Surgery, Third Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650118, ChinaDepartment of Abdominal Surgery, Third Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650118, ChinaDepartment of Abdominal Surgery, Third Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650118, ChinaDepartment of Abdominal Surgery, Third Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650118, ChinaGastric cancer is a malignant tumor with a high degree of malignancy. Multiple liver metastases from gastric cancer (LMGCs) are common. However, the treatment of LMGCs is very difficult. It is rare to achieve complete remission (CR) and long-term survival after treatment. We present the case of a patient with gastric adenocarcinoma and multiple liver metastases who showed CR for more than 33 months after perioperative EOX (epirubicin, oxaliplatin, and capecitabine) combination chemotherapy with radical distal gastrectomy and resection of liver metastases. The patient is still in follow-up without tumor recurrence. These findings suggest that LMGC does not necessarily mean a poor prognosis; preoperative chemotherapy combined with surgery may be a good treatment option for LMGC in selected patients. Further studies are needed to support this treatment approach.http://dx.doi.org/10.1155/2018/3954260 |
| spellingShingle | Zhi-jun Yan Jia-xin Wang You-yi Liu Zhen-hui Li Li-juan Zhang Ping Gan Xiao Han Li-kun Luan You-guo Dai A Case of Complete Remission from Advanced Gastric Adenocarcinoma with Synchronous Liver Metastasis in Response to EOX Chemotherapy Case Reports in Gastrointestinal Medicine |
| title | A Case of Complete Remission from Advanced Gastric Adenocarcinoma with Synchronous Liver Metastasis in Response to EOX Chemotherapy |
| title_full | A Case of Complete Remission from Advanced Gastric Adenocarcinoma with Synchronous Liver Metastasis in Response to EOX Chemotherapy |
| title_fullStr | A Case of Complete Remission from Advanced Gastric Adenocarcinoma with Synchronous Liver Metastasis in Response to EOX Chemotherapy |
| title_full_unstemmed | A Case of Complete Remission from Advanced Gastric Adenocarcinoma with Synchronous Liver Metastasis in Response to EOX Chemotherapy |
| title_short | A Case of Complete Remission from Advanced Gastric Adenocarcinoma with Synchronous Liver Metastasis in Response to EOX Chemotherapy |
| title_sort | case of complete remission from advanced gastric adenocarcinoma with synchronous liver metastasis in response to eox chemotherapy |
| url | http://dx.doi.org/10.1155/2018/3954260 |
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