Intratumor microbiome-derived butyrate enhances progesterone sensitivity by inducing ferroptosis in endometrial cancer
Endometrial cancer (EC) is increasingly affecting younger women, and progesterone therapy remains the cornerstone of fertility-preserving treatment (FPT). However, progesterone resistance presents a major clinical challenge. While the tumor microbiome and its metabolites have been implicated in vari...
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| Main Authors: | Xingchen Li, Yiqin Wang, Yuman Wu, Jingyuan Wang, Yue Qi, Xinyi Bi, Jianliu Wang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-09-01
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| Series: | Pharmacological Research |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1043661825003275 |
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