Pharmacodynamic Model of the Hemodynamic Effects of Propofol and Remifentanil and Their Interaction with Noxious Stimulation

Pharmacodynamic Model of the Hemodynamic Effects of Propofol and Remifentanil and Their Interaction with Noxious Stimulation

<b>Background</b>: Despite the known impact of propofol and remifentanil on hemodynamics and patient outcomes, there is a lack of comprehensive quantitative analysis, particularly in surgical settings, considering the influence of noxious stimuli. The aim of this study was to develop a q...

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Bibliographic Details
Main Authors: Maite Garraza-Obaldia, Sebastian Jaramillo, Zinnia P. Parra-Guillen, José F. Valencia, Pedro L. Gambús, Iñaki F. Trocóniz
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Pharmaceutics
Subjects:
PKPD modelling
population approach
anesthesia
mean arterial pressure
heart rate
hysteroscopy
Online Access:https://www.mdpi.com/1999-4923/16/12/1615
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