Pupil‐sparing cranial nerve III palsy after intranasal cocaine treatment for cluster headache

Abstract This case report discusses a cranial nerve III palsy in a 47‐year‐old, type II diabetic man that originally presented with a cluster headache that was treated with 100% oxygen by nasal cannula, 975 mg Tylenol, and 100 mg of Imitrex without any symptom relief. He then received a sphenopalati...

Full description

Saved in:
Bibliographic Details
Main Authors: Philip M. Davis, Mark L. Riddle
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Journal of the American College of Emergency Physicians Open
Subjects:
Online Access:https://doi.org/10.1002/emp2.12074
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849315646285807616
author Philip M. Davis
Mark L. Riddle
author_facet Philip M. Davis
Mark L. Riddle
author_sort Philip M. Davis
collection DOAJ
description Abstract This case report discusses a cranial nerve III palsy in a 47‐year‐old, type II diabetic man that originally presented with a cluster headache that was treated with 100% oxygen by nasal cannula, 975 mg Tylenol, and 100 mg of Imitrex without any symptom relief. He then received a sphenopalatine fossa block using 1 ampule of 4% cocaine. Three days after medicinal, intranasal cocaine for treatment of a cluster headache, the patient presented with a cranial nerve III palsy with spontaneous resolution in 4 months without any intervention. Previously, intranasal cocaine had been standard treatment for cluster headaches; however, recently lidocaine has come into favor for the sphenopalatine block. Intranasal cocaine has been associated with cerebrovascular accidents, even in young adults. The time from cocaine use to cerebrovascular accident can range from hours to years. This known side effect of intranasal cocaine in young, otherwise healthy individuals should be considered when this medication is being used to treat headache, especially in higher risk patients. Therefore, when considering a sphenopalatine nerve block for treatment of headaches, both cluster and migraine, lidocaine should be the preferential treatment over intra‐nasal cocaine.
format Article
id doaj-art-126cd6cedd1f4bb78bfc38f8c9c2d346
institution Kabale University
issn 2688-1152
language English
publishDate 2020-10-01
publisher Elsevier
record_format Article
series Journal of the American College of Emergency Physicians Open
spelling doaj-art-126cd6cedd1f4bb78bfc38f8c9c2d3462025-08-20T03:52:06ZengElsevierJournal of the American College of Emergency Physicians Open2688-11522020-10-011593593710.1002/emp2.12074Pupil‐sparing cranial nerve III palsy after intranasal cocaine treatment for cluster headachePhilip M. Davis0Mark L. Riddle1Carl R. Darnall Army Medical Center Emergency Department Fort Hood TexasCarl R. Darnall Army Medical Center Emergency Department Fort Hood TexasAbstract This case report discusses a cranial nerve III palsy in a 47‐year‐old, type II diabetic man that originally presented with a cluster headache that was treated with 100% oxygen by nasal cannula, 975 mg Tylenol, and 100 mg of Imitrex without any symptom relief. He then received a sphenopalatine fossa block using 1 ampule of 4% cocaine. Three days after medicinal, intranasal cocaine for treatment of a cluster headache, the patient presented with a cranial nerve III palsy with spontaneous resolution in 4 months without any intervention. Previously, intranasal cocaine had been standard treatment for cluster headaches; however, recently lidocaine has come into favor for the sphenopalatine block. Intranasal cocaine has been associated with cerebrovascular accidents, even in young adults. The time from cocaine use to cerebrovascular accident can range from hours to years. This known side effect of intranasal cocaine in young, otherwise healthy individuals should be considered when this medication is being used to treat headache, especially in higher risk patients. Therefore, when considering a sphenopalatine nerve block for treatment of headaches, both cluster and migraine, lidocaine should be the preferential treatment over intra‐nasal cocaine.https://doi.org/10.1002/emp2.12074cocainecranial nerve III palsycluster headache treatmentoculomotor nerve
spellingShingle Philip M. Davis
Mark L. Riddle
Pupil‐sparing cranial nerve III palsy after intranasal cocaine treatment for cluster headache
Journal of the American College of Emergency Physicians Open
cocaine
cranial nerve III palsy
cluster headache treatment
oculomotor nerve
title Pupil‐sparing cranial nerve III palsy after intranasal cocaine treatment for cluster headache
title_full Pupil‐sparing cranial nerve III palsy after intranasal cocaine treatment for cluster headache
title_fullStr Pupil‐sparing cranial nerve III palsy after intranasal cocaine treatment for cluster headache
title_full_unstemmed Pupil‐sparing cranial nerve III palsy after intranasal cocaine treatment for cluster headache
title_short Pupil‐sparing cranial nerve III palsy after intranasal cocaine treatment for cluster headache
title_sort pupil sparing cranial nerve iii palsy after intranasal cocaine treatment for cluster headache
topic cocaine
cranial nerve III palsy
cluster headache treatment
oculomotor nerve
url https://doi.org/10.1002/emp2.12074
work_keys_str_mv AT philipmdavis pupilsparingcranialnerveiiipalsyafterintranasalcocainetreatmentforclusterheadache
AT marklriddle pupilsparingcranialnerveiiipalsyafterintranasalcocainetreatmentforclusterheadache