Small Vessel Cerebrovascular Disease: The Past, Present, and Future

Brain infarction due to small vessel cerebrovascular disease (SVCD)—also known as small vessel infarct (SVI) or “lacunar” stroke—accounts for 20% to 25% of all ischemic strokes. Historically, SVIs have been associated with a favorable short-term prognosis. However, studies over the years have demons...

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Main Authors: Réza Behrouz, Ali R. Malek, Michel T. Torbey
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Stroke Research and Treatment
Online Access:http://dx.doi.org/10.1155/2012/839151
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author Réza Behrouz
Ali R. Malek
Michel T. Torbey
author_facet Réza Behrouz
Ali R. Malek
Michel T. Torbey
author_sort Réza Behrouz
collection DOAJ
description Brain infarction due to small vessel cerebrovascular disease (SVCD)—also known as small vessel infarct (SVI) or “lacunar” stroke—accounts for 20% to 25% of all ischemic strokes. Historically, SVIs have been associated with a favorable short-term prognosis. However, studies over the years have demonstrated that SVCD/SVI is perhaps a more complex and less benign phenomenon than generally presumed. The currently employed diagnostic and therapeutic strategies are based upon historical and contemporary perceptions of SVCD/SVI. What is discovered in the future will unmask the true countenance of SVCD/SVI and help furnish more accurate prognostication schemes and effective treatments for this condition. This paper is an overview of SVCD/SVI with respect to the discoveries of the past, what is known now, and what will the ongoing investigations evince in the future.
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spelling doaj-art-126900849bb0490c82d709b95f6f7ebc2025-08-20T03:55:44ZengWileyStroke Research and Treatment2090-81052042-00562012-01-01201210.1155/2012/839151839151Small Vessel Cerebrovascular Disease: The Past, Present, and FutureRéza Behrouz0Ali R. Malek1Michel T. Torbey2Division of Cerebrovascular Diseases & Neurocritical Care, Department of Neurology, The Ohio State University College of Medicine, 395 West 12th Avenue, 7th Floor, Suite 766, Columbus, OH 43210, USAInterventional Neurology Program, Comprehensive Stroke Center, St. Mary's Medical Center, 901 45th Street, West Palm Beach, FL 33407, USADivision of Cerebrovascular Diseases & Neurocritical Care, Department of Neurology, The Ohio State University College of Medicine, 395 West 12th Avenue, 7th Floor, Suite 766, Columbus, OH 43210, USABrain infarction due to small vessel cerebrovascular disease (SVCD)—also known as small vessel infarct (SVI) or “lacunar” stroke—accounts for 20% to 25% of all ischemic strokes. Historically, SVIs have been associated with a favorable short-term prognosis. However, studies over the years have demonstrated that SVCD/SVI is perhaps a more complex and less benign phenomenon than generally presumed. The currently employed diagnostic and therapeutic strategies are based upon historical and contemporary perceptions of SVCD/SVI. What is discovered in the future will unmask the true countenance of SVCD/SVI and help furnish more accurate prognostication schemes and effective treatments for this condition. This paper is an overview of SVCD/SVI with respect to the discoveries of the past, what is known now, and what will the ongoing investigations evince in the future.http://dx.doi.org/10.1155/2012/839151
spellingShingle Réza Behrouz
Ali R. Malek
Michel T. Torbey
Small Vessel Cerebrovascular Disease: The Past, Present, and Future
Stroke Research and Treatment
title Small Vessel Cerebrovascular Disease: The Past, Present, and Future
title_full Small Vessel Cerebrovascular Disease: The Past, Present, and Future
title_fullStr Small Vessel Cerebrovascular Disease: The Past, Present, and Future
title_full_unstemmed Small Vessel Cerebrovascular Disease: The Past, Present, and Future
title_short Small Vessel Cerebrovascular Disease: The Past, Present, and Future
title_sort small vessel cerebrovascular disease the past present and future
url http://dx.doi.org/10.1155/2012/839151
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