NOSOTROPIC SUBSTANTIATION OF ANTI IgE ANIBODY THERAPY

This article studies the specifics of allergic diseases pathogenesis. Such common allergic diseases as bronchial asthma, allergic rhinitis and atopic dermatitis are conditioned by processes based on increase of immunoglobulin e synthesis. Omalizunab, which is a recombinant humanized monoclone anti-I...

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Main Author: Yu.G. Levina
Format: Article
Language:Russian
Published: Union of pediatricians of Russia 2008-03-01
Series:Педиатрическая фармакология
Online Access:https://www.pedpharma.ru/jour/article/view/875
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author Yu.G. Levina
author_facet Yu.G. Levina
author_sort Yu.G. Levina
collection DOAJ
description This article studies the specifics of allergic diseases pathogenesis. Such common allergic diseases as bronchial asthma, allergic rhinitis and atopic dermatitis are conditioned by processes based on increase of immunoglobulin e synthesis. Omalizunab, which is a recombinant humanized monoclone anti-Ige antibody, prevents Ige fixing to membrane receptors of mast cells and significantly reduces the level of immunoglobulin e circulating in blood.Key words: anti-Ige antibody, omalizumab, allergic diseases, Bronchial asthma, children.
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institution Kabale University
issn 1727-5776
2500-3089
language Russian
publishDate 2008-03-01
publisher Union of pediatricians of Russia
record_format Article
series Педиатрическая фармакология
spelling doaj-art-125adf090e5f4bb8b1b33da2dbef40ab2025-08-20T03:40:11ZrusUnion of pediatricians of RussiaПедиатрическая фармакология1727-57762500-30892008-03-01524650870NOSOTROPIC SUBSTANTIATION OF ANTI IgE ANIBODY THERAPYYu.G. Levina0Scientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowThis article studies the specifics of allergic diseases pathogenesis. Such common allergic diseases as bronchial asthma, allergic rhinitis and atopic dermatitis are conditioned by processes based on increase of immunoglobulin e synthesis. Omalizunab, which is a recombinant humanized monoclone anti-Ige antibody, prevents Ige fixing to membrane receptors of mast cells and significantly reduces the level of immunoglobulin e circulating in blood.Key words: anti-Ige antibody, omalizumab, allergic diseases, Bronchial asthma, children.https://www.pedpharma.ru/jour/article/view/875
spellingShingle Yu.G. Levina
NOSOTROPIC SUBSTANTIATION OF ANTI IgE ANIBODY THERAPY
Педиатрическая фармакология
title NOSOTROPIC SUBSTANTIATION OF ANTI IgE ANIBODY THERAPY
title_full NOSOTROPIC SUBSTANTIATION OF ANTI IgE ANIBODY THERAPY
title_fullStr NOSOTROPIC SUBSTANTIATION OF ANTI IgE ANIBODY THERAPY
title_full_unstemmed NOSOTROPIC SUBSTANTIATION OF ANTI IgE ANIBODY THERAPY
title_short NOSOTROPIC SUBSTANTIATION OF ANTI IgE ANIBODY THERAPY
title_sort nosotropic substantiation of anti ige anibody therapy
url https://www.pedpharma.ru/jour/article/view/875
work_keys_str_mv AT yuglevina nosotropicsubstantiationofantiigeanibodytherapy