Harnessing miR-16-5p-Loaded Exosomes from Adipose-Derived Stem Cells to Restore Immune Homeostasis in SLE Patients

Harnessing miR-16-5p-Loaded Exosomes from Adipose-Derived Stem Cells to Restore Immune Homeostasis in SLE Patients

Background: Systemic Lupus Erythematosus (SLE) is an autoimmune disorder marked by an imbalance between pro-inflammatory Th17 cells and regulatory T cells (Tregs), which contributes to chronic inflammation and multi-organ damage, necessitating novel therapeutic strategies. Methods: This study invest...

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Bibliographic Details
Main Authors: Yin-hong Zhang, Juan Chen, Wen-fei Mao, Li-xi Yan, Fei Long, Sheng-hao Li, Rui-xian Zhang
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Immunobiology
Subjects:
SLE
ADSC-exos
Th17/Treg
miR-16-5p
LATS1
Online Access:http://www.sciencedirect.com/science/article/pii/S0171298525000191
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