De-novo assembly and comparative analysis of the complete mitogenome of traditional Chinese medicine Strobilanthes sarcorrhiza

Abstract Background Strobilanthes sarcorrhiza is a traditional medicinal plant known for its heat-clearing and kidney-nourishing properties. While its plastid genome has been reported, there is a scarcity of genetic information regarding its mitogenome, leading to unclear phylogenetic relationships....

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Main Authors: Yujie Shi, Ping Li, Jian Sun, Meixin Li, Jingyong Jiang, Yue Xin, Zhen Chen, Wei Zeng
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Plant Biology
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Online Access:https://doi.org/10.1186/s12870-025-06731-3
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author Yujie Shi
Ping Li
Jian Sun
Meixin Li
Jingyong Jiang
Yue Xin
Zhen Chen
Wei Zeng
author_facet Yujie Shi
Ping Li
Jian Sun
Meixin Li
Jingyong Jiang
Yue Xin
Zhen Chen
Wei Zeng
author_sort Yujie Shi
collection DOAJ
description Abstract Background Strobilanthes sarcorrhiza is a traditional medicinal plant known for its heat-clearing and kidney-nourishing properties. While its plastid genome has been reported, there is a scarcity of genetic information regarding its mitogenome, leading to unclear phylogenetic relationships. We sequenced and assembled the complete its mitogenome and conducted a series of genetic analyses in conjunction with the plastid genome to gain a better understanding of the species’ genetic background. Results The mitogenome comprised a linear structure spanning 617,134 bp. It included 35 protein-coding genes (PCGs), 19 transfer RNAs (tRNAs), and 3 ribosomal RNAs (rRNAs) that have been annotated. Additionally, 122 simple sequence repeats (SSRs) and 25 tandem repeats were identified. A total of 1,482 pairs of dispersed repeats were detected, which account for 17.58% of the entire mitogenome. Furthermore, 37 migration fragments between the mitochondrial and plastid genomes were discovered, consisting of 5 complete PCGs, 7 tRNAs, and 1 rRNA. Based on the analysis of 38 mitogenomes and 46 plastid genomes, the evolutionary relationship and phylogenetic position of S. sarcorrhiza were elucidated. Conclusions This study has, for the first time, provided insights into the mitochondrial genomic characteristics of S. sarcorrhiza and clarified its phylogenetic position. These findings offered significant insights for the future identification and classification of this genus, as well as for the genetic breeding of medicinal plants.
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spelling doaj-art-124dcc0a69f649c09ca7b92f90b0dad92025-08-20T01:52:22ZengBMCBMC Plant Biology1471-22292025-05-0125111410.1186/s12870-025-06731-3De-novo assembly and comparative analysis of the complete mitogenome of traditional Chinese medicine Strobilanthes sarcorrhizaYujie Shi0Ping Li1Jian Sun2Meixin Li3Jingyong Jiang4Yue Xin5Zhen Chen6Wei Zeng7Zhejiang Provincial Key Laboratory of Plant Evolutionary Ecology and Conservation, College of Life Sciences, Taizhou UniversityHuangyan Forestry Technology Promotion StationZhejiang Research Institute of Traditional Chinese MedicineZhejiang Provincial Key Laboratory of Plant Evolutionary Ecology and Conservation, College of Life Sciences, Taizhou UniversityInstitute of Horticulture, Taizhou Academy of Agricultural SciencesZhejiang Provincial Key Laboratory of Plant Evolutionary Ecology and Conservation, College of Life Sciences, Taizhou UniversityZhejiang Provincial Key Laboratory of Plant Evolutionary Ecology and Conservation, College of Life Sciences, Taizhou UniversityZhejiang Provincial Key Laboratory of Plant Evolutionary Ecology and Conservation, College of Life Sciences, Taizhou UniversityAbstract Background Strobilanthes sarcorrhiza is a traditional medicinal plant known for its heat-clearing and kidney-nourishing properties. While its plastid genome has been reported, there is a scarcity of genetic information regarding its mitogenome, leading to unclear phylogenetic relationships. We sequenced and assembled the complete its mitogenome and conducted a series of genetic analyses in conjunction with the plastid genome to gain a better understanding of the species’ genetic background. Results The mitogenome comprised a linear structure spanning 617,134 bp. It included 35 protein-coding genes (PCGs), 19 transfer RNAs (tRNAs), and 3 ribosomal RNAs (rRNAs) that have been annotated. Additionally, 122 simple sequence repeats (SSRs) and 25 tandem repeats were identified. A total of 1,482 pairs of dispersed repeats were detected, which account for 17.58% of the entire mitogenome. Furthermore, 37 migration fragments between the mitochondrial and plastid genomes were discovered, consisting of 5 complete PCGs, 7 tRNAs, and 1 rRNA. Based on the analysis of 38 mitogenomes and 46 plastid genomes, the evolutionary relationship and phylogenetic position of S. sarcorrhiza were elucidated. Conclusions This study has, for the first time, provided insights into the mitochondrial genomic characteristics of S. sarcorrhiza and clarified its phylogenetic position. These findings offered significant insights for the future identification and classification of this genus, as well as for the genetic breeding of medicinal plants.https://doi.org/10.1186/s12870-025-06731-3De-novo assemblyStrobilanthes sarcorrhizaMitochondrial genomeMolecular markerChinese medicine identification
spellingShingle Yujie Shi
Ping Li
Jian Sun
Meixin Li
Jingyong Jiang
Yue Xin
Zhen Chen
Wei Zeng
De-novo assembly and comparative analysis of the complete mitogenome of traditional Chinese medicine Strobilanthes sarcorrhiza
BMC Plant Biology
De-novo assembly
Strobilanthes sarcorrhiza
Mitochondrial genome
Molecular marker
Chinese medicine identification
title De-novo assembly and comparative analysis of the complete mitogenome of traditional Chinese medicine Strobilanthes sarcorrhiza
title_full De-novo assembly and comparative analysis of the complete mitogenome of traditional Chinese medicine Strobilanthes sarcorrhiza
title_fullStr De-novo assembly and comparative analysis of the complete mitogenome of traditional Chinese medicine Strobilanthes sarcorrhiza
title_full_unstemmed De-novo assembly and comparative analysis of the complete mitogenome of traditional Chinese medicine Strobilanthes sarcorrhiza
title_short De-novo assembly and comparative analysis of the complete mitogenome of traditional Chinese medicine Strobilanthes sarcorrhiza
title_sort de novo assembly and comparative analysis of the complete mitogenome of traditional chinese medicine strobilanthes sarcorrhiza
topic De-novo assembly
Strobilanthes sarcorrhiza
Mitochondrial genome
Molecular marker
Chinese medicine identification
url https://doi.org/10.1186/s12870-025-06731-3
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