Epigenome-wide DNA methylation profiling in septic and non-septic patients with similar infections: potential use as sepsis biomarkers

Epigenome-wide DNA methylation profiling in septic and non-septic patients with similar infections: potential use as sepsis biomarkers

IntroductionSepsis is a life-threatening condition caused by a dysregulated immune response to infection, leading to organ failure. Despite its significant global burden, the underlying mechanisms of immune dysfunction in sepsis remain incompletely understood. This study explores the role of DNA met...

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Bibliographic Details
Main Authors: Ian López-Cruz, José Luis García-Giménez, Manuel Madrazo, Judit García-Guallarte, Laura Piles, Federico V. Pallardó, Arturo Artero
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
sepsis
septic shock
DNA methylation
epigenetics
biomarkers
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2024.1532417/full
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