Amniotic Fluid β2- Microglobulin Measurements

OBJECTIVE: To determine β2-microglobulin levels in amniotic fluid during the course of second trimester. STUDY DESIGN: One hundred patient’s amniotic fluid β2-microglobulin levels had been evaluated retrospectively (March-October 2009). The most common amniocentesis indication was advanced materna...

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Main Authors: Emine Aydın, Alp Tuna Beksaç, Ergün Karaağaoğlu, M. Sinan Beksaç
Format: Article
Language:English
Published: Medical Network 2015-04-01
Series:Gynecology Obstetrics & Reproductive Medicine
Subjects:
Online Access:https://gorm.com.tr/index.php/GORM/article/view/35
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author Emine Aydın
Alp Tuna Beksaç
Ergün Karaağaoğlu
M. Sinan Beksaç
author_facet Emine Aydın
Alp Tuna Beksaç
Ergün Karaağaoğlu
M. Sinan Beksaç
author_sort Emine Aydın
collection DOAJ
description OBJECTIVE: To determine β2-microglobulin levels in amniotic fluid during the course of second trimester. STUDY DESIGN: One hundred patient’s amniotic fluid β2-microglobulin levels had been evaluated retrospectively (March-October 2009). The most common amniocentesis indication was advanced maternal age (33.3%). Others were; high risk result for triple test (18.5%), high risk result for double test (6.48%), ventriculomegaly (5.55%), obstetric history for fetus with down syndrome (4.62%), the presence of soft markers on ultrasound (13.8%), others (17.8%). Patients average gravida was 2.66 (range: 1-6), parity was 0.75 (range: 0-3), abortion was 0.65 (range: 0-3). RESULTS: All patients were at second trimester and the average gestational week was 17.7 (range 15- 22). Patients were divided into four groups (15th, 16th, 17-18th and 19-20th gestational weeks). We have demonstrated that amniotic fluid β2-microglobulin levels are increased progressively throughout the second trimester. We have specified normal β2-microglobulin values of each gestational week/period in order to be used in clinical practice. CONCLUSION: We have demonstrated that amnionic fluid β2-microglobulin levels are increased progressively throughout the second trimester.
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institution Kabale University
issn 1300-4751
2602-4918
language English
publishDate 2015-04-01
publisher Medical Network
record_format Article
series Gynecology Obstetrics & Reproductive Medicine
spelling doaj-art-123d649f8fc14b10abf55e6c8db54ea82025-02-11T21:25:24ZengMedical NetworkGynecology Obstetrics & Reproductive Medicine1300-47512602-49182015-04-0121130Amniotic Fluid β2- Microglobulin MeasurementsEmine Aydın0Alp Tuna Beksaç1Ergün Karaağaoğlu2M. Sinan Beksaç3Hacettepe University Medical Faculty, Division of Perinatal Medicine, AnkaraHacettepe University Medical Faculty, Department of Urology, AnkaraHacettepe University Medical Faculty, Department of Bioistatistics, AnkaraHacettepe University Medical Faculty, Division of Perinatal Medicine, Ankara OBJECTIVE: To determine β2-microglobulin levels in amniotic fluid during the course of second trimester. STUDY DESIGN: One hundred patient’s amniotic fluid β2-microglobulin levels had been evaluated retrospectively (March-October 2009). The most common amniocentesis indication was advanced maternal age (33.3%). Others were; high risk result for triple test (18.5%), high risk result for double test (6.48%), ventriculomegaly (5.55%), obstetric history for fetus with down syndrome (4.62%), the presence of soft markers on ultrasound (13.8%), others (17.8%). Patients average gravida was 2.66 (range: 1-6), parity was 0.75 (range: 0-3), abortion was 0.65 (range: 0-3). RESULTS: All patients were at second trimester and the average gestational week was 17.7 (range 15- 22). Patients were divided into four groups (15th, 16th, 17-18th and 19-20th gestational weeks). We have demonstrated that amniotic fluid β2-microglobulin levels are increased progressively throughout the second trimester. We have specified normal β2-microglobulin values of each gestational week/period in order to be used in clinical practice. CONCLUSION: We have demonstrated that amnionic fluid β2-microglobulin levels are increased progressively throughout the second trimester. https://gorm.com.tr/index.php/GORM/article/view/35Amniotic fluidβ2-microglobulinSecond trimester
spellingShingle Emine Aydın
Alp Tuna Beksaç
Ergün Karaağaoğlu
M. Sinan Beksaç
Amniotic Fluid β2- Microglobulin Measurements
Gynecology Obstetrics & Reproductive Medicine
Amniotic fluid
β2-microglobulin
Second trimester
title Amniotic Fluid β2- Microglobulin Measurements
title_full Amniotic Fluid β2- Microglobulin Measurements
title_fullStr Amniotic Fluid β2- Microglobulin Measurements
title_full_unstemmed Amniotic Fluid β2- Microglobulin Measurements
title_short Amniotic Fluid β2- Microglobulin Measurements
title_sort amniotic fluid β2 microglobulin measurements
topic Amniotic fluid
β2-microglobulin
Second trimester
url https://gorm.com.tr/index.php/GORM/article/view/35
work_keys_str_mv AT emineaydın amnioticfluidb2microglobulinmeasurements
AT alptunabeksac amnioticfluidb2microglobulinmeasurements
AT ergunkaraagaoglu amnioticfluidb2microglobulinmeasurements
AT msinanbeksac amnioticfluidb2microglobulinmeasurements