Biliopancreatic Diversion: The Effectiveness of Duodenal Switch and Its Limitations
The prevalence of morbidly obese individuals is rising rapidly. Being overweight predisposes patients to multiple serious medical comorbidities including type two diabetes (T2DM), hypertension, dyslipidemia, and obstructive sleep apnea. Lifestyle modifications including diet and exercise produce mod...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2013/974762 |
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| author | Blaire Anderson Richdeep S. Gill Christopher J. de Gara Shahzeer Karmali Michel Gagner |
| author_facet | Blaire Anderson Richdeep S. Gill Christopher J. de Gara Shahzeer Karmali Michel Gagner |
| author_sort | Blaire Anderson |
| collection | DOAJ |
| description | The prevalence of morbidly obese individuals is rising rapidly. Being overweight predisposes patients to multiple serious medical comorbidities including type two diabetes (T2DM), hypertension, dyslipidemia, and obstructive sleep apnea. Lifestyle modifications including diet and exercise produce modest weight reduction and bariatric surgery is the only evidence-based intervention with sustainable results. Biliopancreatic diversion (BPD) produces the most significant weight loss with amelioration of many obesity-related comorbidities compared to other bariatric surgeries; however perioperative morbidity and mortality associated with this surgery are not insignificant; additionally long-term complications including undesirable gastrointestinal side effects and metabolic derangements cannot be ignored. The overall quality of evidence in the literature is low with a lack of randomized control trials, a preponderance of uncontrolled series, and small sample sizes in the studies available. Additionally, when assessing remission of comorbidities, definitions are unclear and variable. In this review we explore the pros and cons of BPD, a less well known and perhaps underutilized bariatric procedure. |
| format | Article |
| id | doaj-art-123741d324344c768347a171abc51848 |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-123741d324344c768347a171abc518482025-08-20T03:54:20ZengWileyGastroenterology Research and Practice1687-61211687-630X2013-01-01201310.1155/2013/974762974762Biliopancreatic Diversion: The Effectiveness of Duodenal Switch and Its LimitationsBlaire Anderson0Richdeep S. Gill1Christopher J. de Gara2Shahzeer Karmali3Michel Gagner4Department of Surgery, University of Alberta, 8440-112 Street, Edmonton, AB, T6G 2B7, CanadaDepartment of Surgery, University of Alberta, 8440-112 Street, Edmonton, AB, T6G 2B7, CanadaDepartment of Surgery, University of Alberta, 8440-112 Street, Edmonton, AB, T6G 2B7, CanadaDepartment of Surgery, University of Alberta, 8440-112 Street, Edmonton, AB, T6G 2B7, CanadaDepartment of Surgery, Hopital Du Sacre Coeur, 191-315 Place D'Youville, Montreal, QC, H2Y 0A4, CanadaThe prevalence of morbidly obese individuals is rising rapidly. Being overweight predisposes patients to multiple serious medical comorbidities including type two diabetes (T2DM), hypertension, dyslipidemia, and obstructive sleep apnea. Lifestyle modifications including diet and exercise produce modest weight reduction and bariatric surgery is the only evidence-based intervention with sustainable results. Biliopancreatic diversion (BPD) produces the most significant weight loss with amelioration of many obesity-related comorbidities compared to other bariatric surgeries; however perioperative morbidity and mortality associated with this surgery are not insignificant; additionally long-term complications including undesirable gastrointestinal side effects and metabolic derangements cannot be ignored. The overall quality of evidence in the literature is low with a lack of randomized control trials, a preponderance of uncontrolled series, and small sample sizes in the studies available. Additionally, when assessing remission of comorbidities, definitions are unclear and variable. In this review we explore the pros and cons of BPD, a less well known and perhaps underutilized bariatric procedure.http://dx.doi.org/10.1155/2013/974762 |
| spellingShingle | Blaire Anderson Richdeep S. Gill Christopher J. de Gara Shahzeer Karmali Michel Gagner Biliopancreatic Diversion: The Effectiveness of Duodenal Switch and Its Limitations Gastroenterology Research and Practice |
| title | Biliopancreatic Diversion: The Effectiveness of Duodenal Switch and Its Limitations |
| title_full | Biliopancreatic Diversion: The Effectiveness of Duodenal Switch and Its Limitations |
| title_fullStr | Biliopancreatic Diversion: The Effectiveness of Duodenal Switch and Its Limitations |
| title_full_unstemmed | Biliopancreatic Diversion: The Effectiveness of Duodenal Switch and Its Limitations |
| title_short | Biliopancreatic Diversion: The Effectiveness of Duodenal Switch and Its Limitations |
| title_sort | biliopancreatic diversion the effectiveness of duodenal switch and its limitations |
| url | http://dx.doi.org/10.1155/2013/974762 |
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