Blue light induced transient localized acne post photodynamic therapy: A case report

Phototherapies including LED light therapy and photodynamic therapy (PDT) are commonly used and considered safe treatment for inflammatory acne. However, there are few reports about the combination of the two methods on the same patient. We report a rare case of blue light induced transient localize...

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Main Authors: Lingbo Du, Xiaoqin Wu, Yinxia Yu, Yao Zhang
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Photodiagnosis and Photodynamic Therapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1572100025000985
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author Lingbo Du
Xiaoqin Wu
Yinxia Yu
Yao Zhang
author_facet Lingbo Du
Xiaoqin Wu
Yinxia Yu
Yao Zhang
author_sort Lingbo Du
collection DOAJ
description Phototherapies including LED light therapy and photodynamic therapy (PDT) are commonly used and considered safe treatment for inflammatory acne. However, there are few reports about the combination of the two methods on the same patient. We report a rare case of blue light induced transient localized acne post PDT. A 32-year-old male with a history of moderate to severe acne for 3 years was successfully treated by 3 sessions of modified red light 5-aminolevulinic acid (ALA) PDT without adverse events during the PDT treatment. However, when he received blue and red LED light therapy as maintenance one week post the last ALA-PDT, severe localized acne burst on his nose. Subsequently, he received single red light treatment for a month, combined with oral administration of doxycycline for the first week. His severe acne on the nose was recovered eventually. No recurrence was observed later.
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series Photodiagnosis and Photodynamic Therapy
spelling doaj-art-122dc951b9ed4d7b9145467e4074babf2025-08-20T03:06:30ZengElsevierPhotodiagnosis and Photodynamic Therapy1572-10002025-06-015310456910.1016/j.pdpdt.2025.104569Blue light induced transient localized acne post photodynamic therapy: A case reportLingbo Du0Xiaoqin Wu1Yinxia Yu2Yao Zhang3Department of Dermatology, Meilong Community Health Service Center of Minhang District, Shanghai, ChinaDepartment of Dermatology, Minhang Hospital, Fudan University, Shanghai, ChinaDepartment of Dermatology, Minhang Hospital, Fudan University, Shanghai, ChinaDepartment of Dermatology, Minhang Hospital, Fudan University, Shanghai, China; Corresponding author at: 170 Xinsong Road, Shanghai 201199, China.Phototherapies including LED light therapy and photodynamic therapy (PDT) are commonly used and considered safe treatment for inflammatory acne. However, there are few reports about the combination of the two methods on the same patient. We report a rare case of blue light induced transient localized acne post PDT. A 32-year-old male with a history of moderate to severe acne for 3 years was successfully treated by 3 sessions of modified red light 5-aminolevulinic acid (ALA) PDT without adverse events during the PDT treatment. However, when he received blue and red LED light therapy as maintenance one week post the last ALA-PDT, severe localized acne burst on his nose. Subsequently, he received single red light treatment for a month, combined with oral administration of doxycycline for the first week. His severe acne on the nose was recovered eventually. No recurrence was observed later.http://www.sciencedirect.com/science/article/pii/S1572100025000985Photodynamic therapyBlue lightAdverse eventAcne
spellingShingle Lingbo Du
Xiaoqin Wu
Yinxia Yu
Yao Zhang
Blue light induced transient localized acne post photodynamic therapy: A case report
Photodiagnosis and Photodynamic Therapy
Photodynamic therapy
Blue light
Adverse event
Acne
title Blue light induced transient localized acne post photodynamic therapy: A case report
title_full Blue light induced transient localized acne post photodynamic therapy: A case report
title_fullStr Blue light induced transient localized acne post photodynamic therapy: A case report
title_full_unstemmed Blue light induced transient localized acne post photodynamic therapy: A case report
title_short Blue light induced transient localized acne post photodynamic therapy: A case report
title_sort blue light induced transient localized acne post photodynamic therapy a case report
topic Photodynamic therapy
Blue light
Adverse event
Acne
url http://www.sciencedirect.com/science/article/pii/S1572100025000985
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AT xiaoqinwu bluelightinducedtransientlocalizedacnepostphotodynamictherapyacasereport
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AT yaozhang bluelightinducedtransientlocalizedacnepostphotodynamictherapyacasereport