Dual-loaded niosome-dendrimer nanoplatform enhances Tirapazamine delivery to hypoxic breast cancer cells

Abstract Breast cancer (BC) is one of the most common cancers in women, requiring comprehensive treatment strategies to reduce disease burden and costs. In this study, we developed an innovative dual nanoparticle system based on niosome containing PAMAM/Tirapazamine (N@P/T), and studied its efficacy...

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Bibliographic Details
Main Authors: Masoumeh Kaveh Zenjanab, Aysan Salemi, Abolfazl Doustmihan, Sajjad Alimohammadvand, Rana Jahanban Esfahlan
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-14704-7
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