Clinico3hemodynamic features of arterial hypertension in patients with metabolic syndrome

The trial included 56 patients (mean age 51.8 ± 0. 8) with metabolic syndome (MS): arterial hypertension - AH (mean stage of AH 11.45 ± 1.1 yrs), non-insuline-dependent diabetes mellitus (mean stage 6. 7+0. 7 yrs), abdominal adiposity, and dyslipidemia. The control group consisted of 22 patients (me...

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Main Authors: L. I. Gapon, I. A. Zhevagina, T. I. Petelina, V. A. Kalinina
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2004-04-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/1951
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author L. I. Gapon
I. A. Zhevagina
T. I. Petelina
V. A. Kalinina
author_facet L. I. Gapon
I. A. Zhevagina
T. I. Petelina
V. A. Kalinina
author_sort L. I. Gapon
collection DOAJ
description The trial included 56 patients (mean age 51.8 ± 0. 8) with metabolic syndome (MS): arterial hypertension - AH (mean stage of AH 11.45 ± 1.1 yrs), non-insuline-dependent diabetes mellitus (mean stage 6. 7+0. 7 yrs), abdominal adiposity, and dyslipidemia. The control group consisted of 22 patients (mean age 49.27 ± 1.78) without metabolic abnormalities. 24-hour BP monitoring was performed in both groups. AH patients with MS demonstrated abnormalities in daily profile of heart rate (HR) and double product (DP, BPx HR/100) during all temporal intervals (whole day, day- and nighttime). This enhanced hemodynamic load on the heart and facilitated progression of left ventricular myocardial hypertrophy (LVMH). Advanced stage of high BP made MS more severe: Stage III AH patients with MS demonstrated significantly greater increase in systolic BP (SBP) (whole day, day- and nighttime) and SBP variability (whole day, day- and nighttime). Therefore, AH is an important factor in MS pathogenesis and progression.
format Article
id doaj-art-122be908d82d4355b28491595b4b04aa
institution Kabale University
issn 1560-4071
2618-7620
language Russian
publishDate 2004-04-01
publisher «FIRMA «SILICEA» LLC
record_format Article
series Российский кардиологический журнал
spelling doaj-art-122be908d82d4355b28491595b4b04aa2025-08-20T03:43:44Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202004-04-010226291709Clinico3hemodynamic features of arterial hypertension in patients with metabolic syndromeL. I. Gapon0I. A. Zhevagina1T. I. Petelina2V. A. Kalinina3Тюменский кардиологический центрТюменский кардиологический центрТюменский кардиологический центрТюменский кардиологический центрThe trial included 56 patients (mean age 51.8 ± 0. 8) with metabolic syndome (MS): arterial hypertension - AH (mean stage of AH 11.45 ± 1.1 yrs), non-insuline-dependent diabetes mellitus (mean stage 6. 7+0. 7 yrs), abdominal adiposity, and dyslipidemia. The control group consisted of 22 patients (mean age 49.27 ± 1.78) without metabolic abnormalities. 24-hour BP monitoring was performed in both groups. AH patients with MS demonstrated abnormalities in daily profile of heart rate (HR) and double product (DP, BPx HR/100) during all temporal intervals (whole day, day- and nighttime). This enhanced hemodynamic load on the heart and facilitated progression of left ventricular myocardial hypertrophy (LVMH). Advanced stage of high BP made MS more severe: Stage III AH patients with MS demonstrated significantly greater increase in systolic BP (SBP) (whole day, day- and nighttime) and SBP variability (whole day, day- and nighttime). Therefore, AH is an important factor in MS pathogenesis and progression.https://russjcardiol.elpub.ru/jour/article/view/1951arterial hypertensionmetabolic syndrome24-hour blood pressure monitoring
spellingShingle L. I. Gapon
I. A. Zhevagina
T. I. Petelina
V. A. Kalinina
Clinico3hemodynamic features of arterial hypertension in patients with metabolic syndrome
Российский кардиологический журнал
arterial hypertension
metabolic syndrome
24-hour blood pressure monitoring
title Clinico3hemodynamic features of arterial hypertension in patients with metabolic syndrome
title_full Clinico3hemodynamic features of arterial hypertension in patients with metabolic syndrome
title_fullStr Clinico3hemodynamic features of arterial hypertension in patients with metabolic syndrome
title_full_unstemmed Clinico3hemodynamic features of arterial hypertension in patients with metabolic syndrome
title_short Clinico3hemodynamic features of arterial hypertension in patients with metabolic syndrome
title_sort clinico3hemodynamic features of arterial hypertension in patients with metabolic syndrome
topic arterial hypertension
metabolic syndrome
24-hour blood pressure monitoring
url https://russjcardiol.elpub.ru/jour/article/view/1951
work_keys_str_mv AT ligapon clinico3hemodynamicfeaturesofarterialhypertensioninpatientswithmetabolicsyndrome
AT iazhevagina clinico3hemodynamicfeaturesofarterialhypertensioninpatientswithmetabolicsyndrome
AT tipetelina clinico3hemodynamicfeaturesofarterialhypertensioninpatientswithmetabolicsyndrome
AT vakalinina clinico3hemodynamicfeaturesofarterialhypertensioninpatientswithmetabolicsyndrome