Respiratory toxicity mechanism of 6PPD and 6PPD-quinone: An integrated study based on network toxicology and molecular docking

Respiratory toxicity mechanism of 6PPD and 6PPD-quinone: An integrated study based on network toxicology and molecular docking

The widespread distribution of environmental contaminants poses a significant threat to public health. N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) and its ozone-derivative, 6PPD-quinone (6PPD-Q), are emerging pollutants that propagate through particulate matter and aerosols, exerting d...

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Bibliographic Details
Main Authors: Gang Li, Dan Li, Weibin Zhai, Chang Liu, Mengying Chen, Qingqiang Xu, Yuanlan Huang
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Ecotoxicology and Environmental Safety
Subjects:
6PPD
6PPD-quinone
Network toxicology
Molecular docking
Respiratory toxicity
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651325008395
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