Fast homozygosity mapping and identification of a zebrafish ENU-induced mutation by whole-genome sequencing.

Fast homozygosity mapping and identification of a zebrafish ENU-induced mutation by whole-genome sequencing.

Forward genetics using zebrafish is a powerful tool for studying vertebrate development through large-scale mutagenesis. Nonetheless, the identification of the molecular lesion is still laborious and involves time-consuming genetic mapping. Here, we show that high-throughput sequencing of the whole...

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Bibliographic Details
Main Authors: Marianne L Voz, Wouter Coppieters, Isabelle Manfroid, Ariane Baudhuin, Virginie Von Berg, Carole Charlier, Dirk Meyer, Wolfgang Driever, Joseph A Martial, Bernard Peers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0034671&type=printable
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