Tumour necrosis factor-alpha (TNFα) stimulates the growth of human bone marrow stromal cells

Tumour necrosis factor-alpha (TNFα) stimulates the growth of human bone marrow stromal cells

This study reports that TNF-α is a potent mitogen for human bone marrow sternal cells in vitro (assessed by [3H]-thymidine incorporation into DNA and cell counts). In contrast, cytokines such as IL-1α, IL-1β, IL-2, IL-3, IL-4, IL-6, LIF, SCF, M-CSF, G-CSF and GM-CSF had no effect. The effect of TNF-...

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Bibliographic Details
Main Authors: F. Rougier, E. Cornu, N. Gachard, V. Praloran, Y. Denizot
Format: Article
Language:English
Published: Wiley 1997-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1080/09629359791730
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